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Structure Department of Biomedical Sciences
Telephone 0498276052
Qualification Professore ordinario
Scientific sector BIO/09 - PHYSIOLOGY
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Office hours
Wednesday from 16:00 to 18:00 Dipartimento di Scienze Biomediche, 2° piano Nord del Complesso Vallisneri Previa E-mail (consigliata in ogni caso) e' possibile fissare un appuntamento in qualsiasi giorno della settimana
(updated on 16/07/2013 11:16)

Curriculum Vitae
Education and training
1979, University of Padova, Degree (Laurea) in Chemistry, Magna cum Laude.
1979-1982, Research Fellow (Lab. Prof. G. Azzone), Institute of General Pathology, University of Padova: Energy transduction in mitochondria.
1984-1985, Postdoctoral Fellow (two EMBO Short Term Fellowships), Dept of Membrane Research (lab. Prof. R. Caplan), Weizmann Institute of Science, Israel: Non-equilibrium thermodynamics of oxidative phosphorylation and kinetic modelling of mitochondrial H+ pumps.
1987-1990, Postdoctoral Fellow (EMBO Long Term Fellowship and Fogarty International Fellowship), Dept of Cellular and Molecular Physiology (Lab Prof P. Hess), Harvard Medical School, U.S.A.: Biophysics of voltage-gated Ca2+ channels.

Employment and Research experience
1983-1991, CNR Researcher, CNR Unit Physiology of Mitochondria, Institute of General Pathology, University of Padova: Energy transduction in mitochondria.
1991-1993, CNR Director of Research, CNR Unit Physiology of Mitochondria, Dept. of Biomedical Sciences, Univ. of Padova: Biophysics and physiology of neuronal Ca2+ channels.
1993-2000 Associate Professor of General Physiology (Faculty of Sciences), Dept. of Biomedical Sciences, Univ. of Padova: Biophysics and physiology of neuronal Ca2+ channels.
2000-, Full Professor of Physiology (Faculty of Sciences), Dept. of Biomedical Sciences, Univ. of Padova: Calcium channelopathies of the central nervous system, in particular familial hemiplegic migraine; pathophysiology of migraine.

Honors and Professional Memberships
1985, Luigi Galvani Prize of the Bioelectrochemical Society.
1996-2000 Member of Council of the Italian Society of Pure and Applied Biophysics
1996-2002 Member of Council of IUPAB (Int. Union of Pure and Applied Biophysics)
2000-2003, Coordinator of the PhD Program in Molecular and Cellular Biology and Pathology of the Univ. of Padova.
2001, National Prize “President of the Republic” in Mathematical, Physical and Natural Sciences awarded by the Accademia dei Lincei
2005-2015, Coordinator of the PhD Program in Neurobiology within the PhD School of Biosciences of the Univ of Padova
2006-2011 Reviewing Editor of “The Journal of Physiology”
2007- Reviewing Editor of “Channels”.
2010-2017 Member of Faculty of 1000
2011- Member of the Venetian Institute of Letters Sciences and Art
2016- Editorial Board of “Neuroscience”
2016- Board of Directors of the Padova Neuroscience Center, University of Padova.
2017- Editorial Board of “European Journal of Physiology”
2018- Editorial Board of "Current Opinion in Neurobiology"

Lecturer's Curriculum (PDF): E11A3A125969DAA9B5651096489DB76B.pdf

Selected publications in last 10 years
1. Brennan KC and Pietrobon D. A systems Neuroscience approach to migraine. (2018) Neuron 97: 1004-1021
2. Pietrobon D. Ion channels in migraine disorders (2018) Curr Opin Physiol 2:98-108
3. Capuani C, Melone M, Tottene A, Bragina L, Crivellaro G, Santello M, Casari G, Conti F and Pietrobon D. Defective glutamate and K+ clearance by cortical astrocytes in familial hemiplegic migraine type 2. (2016) EMBO Mol Med. 8:967-986
4. Vecchia D, Tottene A, van den Maagdenberg AM, Pietrobon D. Abnormal cortical synaptic transmission in CaV2.1 knockin mice with the S218L missense mutation which causes a severe familial hemiplegic migraine syndrome in humans. (2015) Front. Cell. Neurosci. 9:8
5. Pietrobon D and Moskowitz M. Propagation of chaos and commotion in the wake of cortical spreading depression and spreading depolarizations. (2014) Nature Rev. Neurosci. 15:379-393
6. Vecchia D, Tottene A, van den Maagdenberg AM and Pietrobon D. Mechanism underlying unaltered cortical inhibitory synaptic transmission in contrast with enhanced excitatory transmission in CaV2.1 knockin migraine mice (2014) Neurobiol Dis. 69:225-234
7. Pietrobon D and Moskowitz M. Pathophysiology of migraine. (2013) Ann Rev Physiol 75:365-91
8. Vecchia D and Pietrobon D. Migraine: a disorder of brain excitatory-inhibitory balance? (2012) Trends Neurosci. 35:507-520
9. Fioretti B, Catacuzzeno L, Sforna L, Gerke-Duncan MB, van den Maagdenberg AM, Franciolini F, Connor M, Pietrobon D. Trigeminal ganglion neuron subtype-specific alterations of Ca(V)2.1 calcium current and excitability in a Cacna1a mouse model of migraine. (2011) J Physiol 589: 5879-5895
10. Leo L, Gherardini L, Barone V, De Fusco M, Pietrobon D, Pizzorusso T, Casari G. Increased susceptibility to cortical spreading depression in the mouse model of familial hemiplegic migraine type 2. (2011) PLoS Genet 7(6): 1-12
11. Tottene A, Urbani A, Pietrobon D (2011) Role of different voltage-gated Ca2+ channels in cortical spreading depression. Specific requirement of P/Q-type Ca2+ channels. (2011) Channels 5: 110-114
12. Van den Maagdenberg AMJM*, Pizzorusso T, Kaja S, Terpolilli N, Shapovalova M, Hoebeek FE, Barrett CF, Gherardini L, van de Ven RC, Todorov B, Broos LAM, Tottene A, Gao Z, Fodor M, De Zeeuw CI, Frants RR, Plesnila N, Plomp JJ, Pietrobon D* and Ferrari MD. High cortical spreading depression susceptibility and migraine-associated symptoms in CaV2.1 S218L mice. (2010) Ann. Neurol. 67:85-98.* Shared corresponding authorship
13. Pietrobon D CaV2.1 channelopathies. (2010) Pfluegers Arch. 460:375-393.
14. Pietrobon D Insights into migraine mechanisms and CaV2.1 channel function from animal models of familial hemiplegic migraine. (2010) J Physiol 588: 1871-1878
15. Tottene A, Conti R, Fabbro A, Vecchia D, Shapovalova M, Santello M, van den Maagdenberg AMJM, Ferrari M and Pietrobon D. Enhanced excitatory transmission at cortical synapses as the basis for facilitated spreading depression in CaV2.1 knockin migraine mice. Neuron (2009) 61:762-773
16. Catterall WA, Dib-Hajj S, Meisler MH and Pietrobon D Inherited Neuronal Ion Channelopathies: New Windows on Complex Neurological Diseases. (2008) J. Neurosci. 28:11768-777
17. Catacuzzeno L, Fioretti B, Pietrobon D and Franciolini F The differential expression of low-threshold K+ currents generates distinct firing patterns in different subtypes of adult mouse trigeminal ganglion neurones. (2008) J. Physiol.586:5101-5118

Lecturer's Publications (PDF): E11A3A125969DAA9B5651096489DB76B.pdf

List of taught course units in A.Y. 2019/20
Degree course code (?) Degree course track Course unit code Course unit name Credits Year Period Lang. Teacher in charge
IN2374 COMMON INP7078929 9 1st Year (2019/20) Second
SC1166 COMMON SC04103235 11 3rd Year (2019/20) Annual ITA MARCO BISAGLIA
SC2445 COMMON SCP8085065 10 1st Year (2019/20) Second