FILIPPINI RAFFAELLA

Contacts
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Structure Department of Pharmaceutical and Pharmacological Sciences
Telephone 049 8275371
Qualification Professore associato confermato
Scientific sector BIO/15 - PHARMACEUTIC BIOLOGY
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Office hours
Il docente riceve gli studenti ogni giorno previa comunicazione tramite e-mail.
Every day by e-mail appointment.
(updated on 26/04/2018 12:31)

Proposals for thesis
Positions for experimental and article-based theses are available. The main experimental activities concern plant cell cultures, and medicinal and food plant study. Self-proposed article-based thesis arguments are also welcome. Contact us for more informations.

Curriculum Vitae
Raffaella Filippini - Associate Professor of Pharmaceutical Biology (SSD BIO/15).

1988 graduated at the University of Padova (Faculty of Pharmacy) with a degree in Pharmacy
1987-1988 Guest researcher at Laboratory of Mass Spectrometry dr. Traldi, CNR (Padova)
1991-1992 Guest researcher at Ecole Nationale Superieure d'Agronomie et des Industries Alimentaires Prof. Bourgaud - Nancy France
1990 Researcher in Faculty of Pharmacy at Padua University
from 2006 Associated Professor at the Faculty of Pharmacy of University of Padua

Member of the Accreditation and Assessment Group (GAV) for degree course in Applied and Pharmaceutical Sciences.

Member of Società Italiana di Fitochimica (SIF) and Società Italiana di Fitoterapia (SIFit).

Author of publications of international and national journals.
Her main scientific interests are in the field of medicinal plants with the following research lines:
- morphological and chemical characterization of plants with pharmaceutical and toxicological interest;
- chemical characterization and identification of new natural source of biologically active compounds;
- biosynthesis and accumulation of natural products in plant cell cultures;
- development of new analysis approaches for natural products;
- in vitro secondary metabolites production and micropropagation of medicinal plants;
- characterization of enzymatic activity in plant cell culture to obtain valuable derivatives with industrial prospects.

Research areas
1. Plants both as source of important secondary metabolites useful for pharmaceutical purposes and as food ingredients with the following research lines:

- identification and chemical characterization of new natural source of biologically active compounds;
- development of new analysis approaches for natural products;
- use sustainable and conservation solutions: biosynthesis and accumulation of natural products in in vitro cell cultures, development of systems for in vitro secondary metabolites production, and micropropagation of medicinal and endangered plants;
- morphological, histochemical, ultrastructural and chemical characterization of plants with pharmaceutical/food and toxicological interest;
- characterization of enzymatic activity in plant cell culture to obtain valuable derivatives with industrial prospects;
- in vitro biocatalysis and enzyme production to develop processes in enabling green chemistries;

2. Algae both as food resource and raw material for obtaining phytochemicals.

Publications
Marzocchi M, Badocco D, Piovan A, Pastore P, Di Marco V, Filippini R, Caniato R (2016) Metals in Undaria pinnatifida (Harvey) Suringar and Sargassum muticum (Yendo) Fensholt edible seaweeds growing around Venice (Italy). Journal of Applied Phycology 28 (4), pp. 2605-2613.

Catanzaro D, Filippini R, Vianello C, Carrara M, Ragazzi E, Montopoli M (2016) Chlorogenic acid interaction with cisplatin and oxaliplatin: Studies in cervical carcinoma cells. Natural Product Communications 11(4):499-502.

Matozzo V, De Notaris C, Finos L, Filippini R, Piovan A (2015) Environmentally realistic concentrations of the antibiotic Trimethoprim affect haemocyte parameters but not antioxidant enzyme activities in the clam Ruditapes philippinarum. Environmental Pollution 206:567-574.

Piovan A, Caniato R, Filippini R, Chiesura F, Dalla Vecchia F (2015) Morphological and phytochemical aspects of three alien Opuntia species on Euganean Hills in North-Eastern Italy. Plant Biosystems 149(4):788-796.

Piovan A, Caniato R, Filippini R (2014) Somatic embryogenesis and glucosinolate/myrosinase system in vulnerable Brassica repanda subsp. glabrescens (Poldini) Gómez-Campo. Scientia Horticulturae 172:317-324.

Piovan A, Filippini R, Innocenti G (2014) Coumarin compounds in Coronilla scorpioides callus cultures. Natural Product Communications 9(4):489-492.

Piovan A, Filippini R, Paoli MD, Bresin B (2014) TLC densitometric method for the preliminary evaluation of fucoxanthin-based products. Natural Product Research 28(14):1111-1115.

Piovan A, Seraglia R, Bresin B, Caniato R, Filippini R (2013) Fucoxanthin from undaria pinnatifida: Photostability and coextractive effects. Molecules 18(6):6298-6310.

Piovan A, Filippini R, Caniato R (2013) Crambe tataria: The Glucosinolate/myrosinase System in vivo and in vitro. Natural Product Communications 8(11):1615-1616.

Filippini R, Piovan A, Caniato R (2011) Substitution of Vaccinium myrtillus L. for Aronia melanocarpa (Michx.) Elliott in a commercial batch. Plant Biosystems 145(1):175-181.

Piovan A, Cassina G, Filippini R (2011) Crambe tataria: Actions for ex situ conservation. Biodiversity and Conservation 20(2):359-371.

Piovan A, Filippini R, Caniato R (2010) A semi-quantitative FIA-ESI-MS method for the rapid screening of Hypericum perforatum crude extracts. Natural Product Communications 5(3):431-434.

Piovan A, Cozza G, Caniato R, Moro S, Filippini R (2010) A novel glucosyltransferase from Catharanthus roseus cell suspensions. Process Biochemistry 45(5):655-659.

Filippini R, Piovan A, Borsarini A, Caniato R (2010) Study of dynamic accumulation of secondary metabolites in three subspecies of Hypericum perforatum. Fitoterapia 81(2):115-119.

Piovan A, Caniato R, Cappelletti EM, Filippini R (2010) Organogenesis from shoot segments and via callus of endangered Kosteletzkya pentacarpos (L.) Ledeb. Plant Cell, Tissue and Organ Culture 100(3):309-315.

Andreola B, Piovan A, Da Dalt L, Filippini R, Cappelletti E (2008) Unilateral mydriasis due to Angel's Trumpet. Clinical Toxicology 46(4):329-331.

List of taught course units in A.Y. 2019/20
Degree course code (?) Degree course track Course unit code Course unit name Credits Year Period Lang. Teacher in charge
FA0243 COMMON MEP4068015   ITA ROSAMARIA CANIATO
»   MEP4068016 10 2nd Year (2019/20) Annual ITA ROSAMARIA CANIATO
»   MEP4068017 6 2nd Year (2019/20) Annual ITA EUGENIO RAGAZZI
FA1732 COMMON MEP3051906 6 5th Year (2019/20) First
semester
ITA RAFFAELLA FILIPPINI
FA0243 COMMON MEP4068018   ITA RAFFAELLA FILIPPINI
»   MEP4068020 6 3rd Year (2019/20) Second
semester
ITA RAFFAELLA FILIPPINI
»   MEP4068019 6 3rd Year (2019/20) Second
semester
ITA MONICA MONTOPOLI


Responsibility of other activity for A.Y. 2019/20
Degree course code (?) Degree course track Course unit code Course unit name Credits Year Period Lang. Teacher in charge
FA0243 COMMON FAM0013121 12 3rd Year (2019/20) Annual ITA RAFFAELLA FILIPPINI