ALVISI GUALTIERO

Contacts
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Structure Department of Molecular Medicine
Telephone 0498272353
Qualification Ricercatore universitario confermato
Scientific sector MED/07 - MICROBIOLOGY AND CLINICAL MICROBIOLOGY
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Proposals for thesis
Projects are available in the following topics

* Nucleocytoplasmic transport of proteins involved in endocytosis

* Development of antiviral drugs and characterization of the mechanism of action

* Regulation of the nuclocytoplasmic transport process

Students will learn the following methods

* cell culture

* molecular cloning, PCR, cloninig gateway, restriction profile analysis

* Western Blotting

* Immunofluorescence

* FACS

* Quantitative analysis of data

* BRET

* FRET

* Laser Confocal Microscopy

* Live cell imaging

Curriculum Vitae
Gualtiero Alvisi obtained his PhD Molecular and Cellular Biotechnologies from Bologna University, Italy in 2005. During is PhD and his subsequent PostDoctoral studies he worked for 3 years in the group of Prof. David Jans, Department of Biochemistry and Molecular Biology at Monash University (Clayton, Victoria, Australia).

In 2007, he returned University of Bologna to continue his studies on Herpesviridae DNA polymerases under the supervision of Dott. Alessandro Ripalti, at the Department of Specialistic and Experimental Medicine.

In 2009 he moved to University of Heidelberg to join the group of Prof. Ralf Bartenchlager at the Department of Molecular Virology and study the relationship between Dengue and Hepatitis C Virus and the host cell, focusing on the identification of host factors important for viral replication and lipid metabolism.

Since 2011 he is an Assistant Professor of Microbiology at University of Padua where he moved to establish his own research group at the Department of Molecular Medicine (http://gualtax.wixsite.com/alvisilab; orcid: https://orcid.org/0000-0002-8177-3616).

The focus of Gualtiero's research is the relationship between infectious agents and infected cells, with particular attention to protein-protein interactions allowing virus replication and promoting disease establishment.

Current projects include the identification of small molecules disrupting protein-protein interactions important for Human Cytomegalovirus replication, characterization of protein-protein interactions involved in Hepatitis C Virus pathogenesis, and studies aiming at elucidating the molecular basis for nuclear transport regulation and specificity.

Gualtiero collaborates with research groups within Italy (University of Bologna, University of Modena, University of Brescia) and internationally (Australia: Monash University, Canberra University, Wagga Wagga University) and his research is funded by PRIN and University of Padua research grants.

He is author of 40 scientific publications in peer-reviewed Journals, including Nature, Cell Host and Microbe Journal of Virology and FASEB, as well as two book chapters (google scholar citations: 989, h-index: 18; https://scholar.google.it/citations?user=s0rZexkAAAAJ&hl=it).

Gualtiero is also deeply involved in peer reviewing (https://publons.com/author/272395/gualtiero-alvisi#profile), being an Editor for PLOS ONE and having reviewed for several Journals including Journal of Virology, Journal of Physiology, Biochemistry, Traffic, Analytical Chemistry and many other Journals.

Lecturer's Curriculum (PDF): 8285600C296C22C13A4ECBBCE92D3AB3.pdf

Research areas
Sono disponibili testi di laurea nei seguenti argomenti

* Trasporto nucleocitoplasmatico di proteine coinvolte nell'endocitosi

* Sviluppo di farmaci antivirali e caratterizzazione del meccanismo d'azione

* Regolazione del processo di trasporto nuclocitoplasmatico

Publications


Lecturer's Publications (PDF): 8285600C296C22C13A4ECBBCE92D3AB3.pdf

List of taught course units in A.Y. 2018/19
Degree course code (?) Degree course track Course unit code Course unit name Credits Year Period Lang. Teacher in charge
ME1853 COMMON MEN1033430 7 1st Year Second
semester
ITA
ME1844 999PD MEP4063586 6 1st Year Second
semester
ITA ANDREA RASOLA
ME1726 COMMON MEP5071038 11 2nd Year Second
semester
ITA IGNAZIO CASTAGLIUOLO