IOP LAURA

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Structure Department of Cardiac, Thoracic and Vascular Sciences
Qualification Ricercatore a tempo determinato di tipo A
Scientific sector MED/46 - LABORATORY MEDICINE TECHNIQUES
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Proposals for thesis
Sono disponibili tesi di laurea in Medicina Rigenerativa Cardiovascolare per la formulazione di nuovi approcci terapeutici funzionali e biocompatibili. Contattare la Dr.ssa Laura Iop (laura.iop@unipd.it) per maggiori informazioni.

Curriculum Vitae
IOP LAURA
Scientific Curriculum

Master degree in Medical Biotechnologies, 2005
Phd in Clinical and Experimental, Medical Sciences, Curriculum of Cardiovascular Sciences, 2010

2005-2007 Graduate Fellowship in Heart Valve Regenerative Medicine, Dept. of Biomedical Sciences, University of Padua
2010-2012 Junior post-doc in Myocardial Regenerative Medicine, Dept. of Cardiac, Thoracic and Vascular Sciences, University of Padua
2010-2012 Post-doc in Cardiac Disease Modeling, Dept. of Molecular Cardiology, Technical University of Munich
2013- Scientific coordinator of the group of Cardiovascular Regenerative Medicine, Dept. of Cardiac, Thoracic and Vascular Sciences, University of Padua
2013-2014 Senior Post-doc in Cardiovascular Regenerative Medicine, Dept. of Cardiac, Thoracic and Vascular Sciences, University of Padua
2015-2016 Post-doc fellowship in Cardiovascular Regenerative Medicine, University Hospital of Padua and Venetian Institute of Molecular Medicine, Padua
2016- Assistant Professor in Medical Technical Sciences, Dept. of Cardiac, Thoracic and Vascular Sciences, University of Padua

2013-2016 Investigator of the FP7 European Project TECAS for the generation of tissue-engineered cardiovascular therapeutic solutions

Teaching activity:
- Co-tutor ‘Cardiovascular Regenerative Medicine’, Master Course in Medicine and Surgery and in Biotechnology, University of Padua, since 2005
- ‘Translational Regenerative Medicine’, Master Course in Medicine and Surgery and in Biotechnology, University of Padua, since 2016
- ‘Cardiac Tissue Engineering’, European Association Cardio-Thoracic Surgery Academy. Since 2012
- ‘Biomedicine’ in 'Medical Semeiotic and Clinical Methodology', Master Course in Medicine and Surgery, University of Padua, since 2017

Member of the Scientific Society ‘Society of Biomechanics’ since 2015
Member of the Scientific Society ‘Scietà Italiana di Cardiochirurgia’ since 2018

Reviewer for Nature Regenerative Medicine, Acta Biomaterialia, Cytotechnology, Journal of Heart Valve Disease, Biomaterials, Journal of Cardiovascular Translational Research.

Editorial board member of Journal of Cardiovascular Translational Research

Author of 34 publications (30 indexed), and of three book chapters. Current H-index: 12. Citation number: 666

Publications
Selected:

1: Iop L, et al. Xenotransplantation: The Way beyond and Ahead toward Clinical Application. J Immunol Res. 2018 Apr 4;2018:6191359.

2: Iop L, et al. The Rapidly Evolving Concept of Whole Heart Engineering. Stem Cells Int. 2017;2017:8920940.

3: Iop L, et al. The Light and Shadow of Senescence and Inflammation in Cardiovascular Pathology and Regenerative Medicine. Mediators Inflamm. 2017;2017:7953486.

4: Gallo M, et al. The Vietnamese pig as a translational animal model to evaluate tissue engineered heart valves: promising early experience. Int J Artif Organs. 2017 May 9;40(4):142-149.

5: Iop L, et al. Decellularized Cryopreserved Allografts as Off-the-Shelf Allogeneic Alternative for Heart Valve Replacement: In Vitro Assessment Before Clinical Translation. J Cardiovasc Transl Res. 2017 Apr;10(2):93-103.

6: Gallo M, al. Decellularized aortic conduits: could their cryopreservation affect post-implantation outcomes? A morpho-functional study on porcine homografts. Heart Vessels. 2016 Nov;31(11):1862-1873.

7: Iop L, et al. Guided tissue regeneration in heart valve replacement: from preclinical research to first-in-human trials. Biomed Res Int. 2015;2015:432901.

8: Iop L, et al. Decellularized allogeneic heart valves demonstrate self-regeneration potential after a long-term preclinical evaluation. PLoS One. 2014 Jun 18;9(6):e99593.

9: Jung CB, et al. Dantrolene rescues arrhythmogenic RYR2 defect in a patient-specific stem cell model of catecholaminergic polymorphic ventricular tachycardia. EMBO Mol Med. 2012 Mar;4(3):180-91.

10: Iop L, et al. The influence of heart valve leaflet matrix characteristics on the interaction between human mesenchymal stem cells and decellularized scaffolds. Biomaterials. 2009 Sep;30(25):4104-16.

11: Rattazzi M, et al. Clones of interstitial cells from bovine aortic valve exhibit different calcifying potential when exposed to endotoxin and phosphate. Arterioscler Thromb Vasc Biol. 2008 Dec;28(12):2165-72.

12: Iop L, et al. Different cardiovascular potential of adult- and fetal-type mesenchymal stem cells in a rat model of heart cryoinjury. Cell Transplant. 2008;17(6):679-94.

List of taught course units in A.Y. 2018/19
Degree course code (?) Degree course track Course unit code Course unit name Credits Year Period Lang. Teacher in charge
ME1726 COMMON MEP8085342 4 1st Year First
semester
ENG LAURA IOP