First cycle
degree courses
Second cycle
degree courses
Single cycle
degree courses
School of Science
NATURAL SCIENCE
Course unit
CHEMISTRY AND BIOCHEMISTRY
SCN1031971, A.A. 2019/20

Information concerning the students who enrolled in A.Y. 2019/20

Information on the course unit
Degree course First cycle degree in
NATURAL SCIENCE
SC1161, Degree course structure A.Y. 2008/09, A.Y. 2019/20
N0
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Number of ECTS credits allocated 8.0
Type of assessment Mark
Course unit English denomination CHEMISTRY AND BIOCHEMISTRY
Website of the academic structure http://scienzenaturali.scienze.unipd.it/2019/laurea
Department of reference Department of Biology
Mandatory attendance
Language of instruction Italian
Branch PADOVA
Single Course unit The Course unit can be attended under the option Single Course unit attendance
Optional Course unit The Course unit can be chosen as Optional Course unit

Lecturers
Teacher in charge ELENA ZIVIANI BIO/10
Other lecturers BARBARA SCOLARO CHIM/06

ECTS: details
Type Scientific-Disciplinary Sector Credits allocated
Educational activities in elective or integrative disciplines BIO/10 Biochemistry 4.0
Basic courses CHIM/06 Organic Chemistry 4.0

Course unit organization
Period Annual
Year 1st Year
Teaching method frontal

Type of hours Credits Teaching
hours
Hours of
Individual study
Shifts
Practice 1.0 12 13.0 No turn
Laboratory 0.5 8 4.5 No turn
Lecture 6.5 52 110.5 No turn

Calendar
Start of activities 30/09/2019
End of activities 20/06/2020
Show course schedule 2019/20 Reg.2008 course timetable

Examination board
Board From To Members of the board
8 CHIMICA ORGANICA E BIOCHIMICA 2019-2020 01/10/2019 27/11/2020 ZIVIANI ELENA (Presidente)
SCOLARO BARBARA (Membro Effettivo)
7 CHIMICA ORGANICA E BIOCHIMICA 01/10/2018 30/11/2019 ZIVIANI ELENA (Presidente)
SCOLARO BARBARA (Membro Effettivo)
CENDRON LAURA (Supplente)

Syllabus
Prerequisites: For the Organic Chemistry module:
General and Inorganic Chemistry.

For the Biochemistry module:
Basic knowledge of General Chemistry and Organic Chemistry.
Target skills and knowledge: For the Organic Chemistry module:
learning of the fundamental principles of Organic Chemistry and of the most important biological molecules chemical properties.

For the Biochemistry module:
acquisition of basic knowledge about structure and operation of bioligical molecules. Knowledge of major metabolic pathways and their regulation.
Examination methods: For the Organic Chemistry module:
written test with open questions.

For the Biochemistry module:
written test (mainly multiple choice questions).
Assessment criteria: Both modules:
student's evaluation will be based upon both comprehensions of topics covered and acquisition of concepts and proposed methodologies.
Course unit contents: For the Organic Chemistry module:
- Chemical bonds
Ionic, covalent and polar covalent bonds. Hydrogen bridges.
- Carbon chemistry
Carbon hybridization
- Alkanes and cycloalkanes
Nomenclature and properties. Cyclohexane conformation.
- Alkenes
Nomenclature and properties. Features and structure.
Reactivity: electrofilic addition. Dienes. Introduction to resonance.
- Alkynes
Nomenclature. Structure, properties and reactivity.
- Benzene and aromaticity
Resonance. Nomenclature and features. Benzene reactivity. Aromatic electrofilic substitutions; substituents influence. Aromatic eterocycles of biologyc relevance.
- Stereoisomerism
Chirality. Optical activity of stereoisomers. Fischer's projections.
- Alkyl halides
Nomenclature and properties. Reactivity: nucleophylic substitutions and eliminations. Mechanisms.
- Alcohols, phenols and ethers.
Alcohols and phenols: nomenclature and properties, acid-base properties and reactivity.
Ethers: nomenclature and properties.
- Carbonyl compounds
Nomenclature and properties. Reactivity: nucleophylic addiction. Keto- enol tautomerism
- Carbohydrates
Monosaccharides. Aldoses: stereoisomerism. Mutarotation, hemiacetals and glycosides. Disaccharides, properties. Polysaccharides. Starch and cellulose, properties and derivatives.
- Carboxylic acids
Nomenclature and properties. Reactivity: acid-base behaviour, nucleophylic substitution. Carboxylic acids derivatives, hydrolysis reactions.
- Lipids
Triglycerides. Saponification. Soaps and detergents. Waxes. Phospholipids. Steroids.
- Amines and amides
Amines: nomenclature and properties. Reactivity: amines as bases and as nucleophyles. Porphyrins. Amides, properties. Aminoacids. Peptydic bond.
- Proteins
Primary, secondary, tertiary and quaternary structures.
- Nucleic acids
Structure. DNA's double helix. DNA's duplication.


For the Biochemistry module:
- Macromolecules structure.
- Carbohydrates: monosaccharides and derivatives; oligosaccharides, polysaccharides.
- Triglycerides and phosphoglycerides structure.
- Proteins. Peptidic bond and peptides, structural hierarchy. Evolutionary importance of primary structures. Secondary structure. Tertiary structure and domains. Quaternary structure.
- Posttranslational modification.
- Enzymes: classification, enzymatic catalysis, enzymatic inhibition.
- pH effects on enzymatic activity.
- Major metabolic pathways and their interconnections
- Carbohydrates metabolism: glucose transport system, glycolysis, pyruvate oxidation, Krebs cycle.
- Lipids metabolism.
- Mitochondrial bioenergetics.
- Respiratory complexes and electron transport chain.
- Chemiosmotic theory and ATP synthesis.
- Photosynthesis.
Planned learning activities and teaching methods: For the Organic Chemistry module:
class teaching and exercises.

For the Biochemistry module:
class teaching and exercises; a laboratory practice is also scheduled, concerning one of the topics covered.
Additional notes about suggested reading: For the Organic Chemistry module:
Harold Hart
"Organic Chemistry" or equivalent.

Lecture notes will be available.

For the Biochemistry module:
David L Nelson, Michael M Cox
"Introduzione alla biochimica di Lehninger"
Quarta edizione Trad. di P.L. Ipata, P. Capini, E. Regola, rev. di E. Melloni, F. Salamino
2011
Ed. Zanichelli

John L Tymoczko, Jeremy M Berg, Lubert Stryer
"Principi di biochimica"
Ed. Zanichelli
Textbooks (and optional supplementary readings)

Innovative teaching methods: Teaching and learning strategies
  • Interactive lecturing
  • Working in group
  • Questioning
  • Problem solving
  • Use of online videos

Innovative teaching methods: Software or applications used
  • Moodle (files, quizzes, workshops, ...)

Sustainable Development Goals (SDGs)
Good Health and Well-Being Quality Education Gender Equality