First cycle
degree courses
Second cycle
degree courses
Single cycle
degree courses
School of Medicine
Course unit
MEN1033926, A.A. 2019/20

Information concerning the students who enrolled in A.Y. 2019/20

Information on the course unit
Degree course First cycle degree in
ME1854, Degree course structure A.Y. 2011/12, A.Y. 2019/20
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Number of ECTS credits allocated 6.0
Type of assessment Mark
Department of reference Department of Neurosciences
Mandatory attendance
Language of instruction Italian
Single Course unit The Course unit CANNOT be attended under the option Single Course unit attendance
Optional Course unit The Course unit is available ONLY for students enrolled in DENTAL HYGIENE

Teacher in charge DAVIDE ANTONIO ABATE MED/07

ECTS: details
Type Scientific-Disciplinary Sector Credits allocated
Core courses MED/07 Microbiology and Clinical Microbiology 6.0

Course unit organization
Period Second semester
Year 1st Year
Teaching method frontal

Type of hours Credits Teaching
Hours of
Individual study
Lecture 6.0 60 90.0 No turn

Start of activities 02/03/2020
End of activities 12/06/2020
Show course schedule 2019/20 Reg.2011 course timetable

Examination board
Board From To Members of the board
DE FILIPPIS COSIMO (Membro Effettivo)

Prerequisites: The student is expected to have knowledge of cell biology and biochemistry
Target skills and knowledge: The student shall learn the major notions on microbes and infectious agents, the hygiene and disinfection and sterilization measures and system of prevention and transmission of infectious agents. The student shall also be familiar with antimicrobial agents and knowledge on microbe resistance to antimicrobial agents.
Course unit contents: - The microbiota in the environment.
- The microbes and humans. Microbial classification : viruses, bacteria, protozoa , fungi , parasites, prions.
- microbe-host interactions: parasitism , commensalism , mutualism . The microbial colonization .
- Principles of microbial pathogenicity .
- Routes of transmission of infectious agents
- Bacteria : morphology and structure of bacterial aggregations. Bacterial ultrastructure: the capsule, fimbriae and pili , cell wall, ribosomes , chromosomal and extrachromosomal DNA , flagella and structures of bacterial locomotion .
- The bacterial metabolism : nutritional requirements in relation to the environment aerobic / anaerobic conditions.
- The bacterial spore: generation and spore germination .
- Microbes vs humans: anatomical defenses , non-specific defenses, the innate and adaptive immune system .
- Serums and vaccines. Principles of prophylaxis and prevention.
- Bacterial toxins . Exotoxins and endotoxins . Tetanus and botulinum neurotoxins . Cholera toxin and enterotoxin . Anthrax , diphtheria toxins. Microbial superantigens . Adhesins and invasines.
- Antibiotics : classification, structure , spectrum , bacteriostatic / bactericidal activity. Target and toxicity of antibiotics . --Association of antibiotic drugs : principles and effects.
- Microbial resistance to antibiotics : prevalence , consequences and molecular mechanism of antibiotic resistance spreading in nosocomial environment . Microbial genetics: conjugation , transformation , transduction . The antibiotic susceptibility testing.
- Viruses : general characteristics and Baltimore classification. The viral replication cycle.
-Virus and carcinogenesis.
- Antiviral drugs: general characteristics and specificity. Resistance to antiviral drugs.
- Transmission , pathogenesis, prevention and tropism of pathogenic human viruses : HIV , HPV, hepatitis viruses. Enteric viruses , herpes virus , respiratory viruses . Viruses transmitted by arthropods vectors.
- The congenital infections , perinatal and postnatal,
- Sexually transmitted diseases.
- Exanthematous infections of childhood.
- Respiratory infections . Pulmonary TB and extrapulmonary
- Infections transmitted by insects and ticks : TBE , Lyme borreliosis , West Nile Virus and emerging infections . Malaria .
- Bacterial and viral infections of the central nervous system. Prions and neurodegenerative infections .
- The morphological and structural characteristics of fungi and fungal infections . Skin fungal infections and diffused infections . -Antifungal drugs and their action.
- Protozoa and parasites : morphological and structural . Anti-protozoal drugs.
- Microbiota of the oral cavity . The microbial biofilms . Microbiological aspects of caries, plaque, tartar , gingivitis, stomatitis , abscesses . Antimicrobial therapy : empirical guidelines . Microbes in the oral cavity , endocarditis, bone infections , brain abscesses .
- Laboratory Diagnosis of microbial infections : Gram stain , trichrome , acid resistant stains. Microbial culture media . Selective media . Cell culture and production of viruses. Direct and indirect diagnostic systems . Serology . Molecular diagnostics and amplification of nucleic acids. Specificity and sensitivity . Common errors in diagnosis of infection.
Textbooks (and optional supplementary readings)