First cycle
degree courses
Second cycle
degree courses
Single cycle
degree courses
School of Medicine
PHARMACY
Course unit
ORGANIC CHEMISTRY
FA04101354, A.A. 2019/20

Information concerning the students who enrolled in A.Y. 2019/20

Information on the course unit
Degree course 5 years single cycle degree in
PHARMACY (Ord. 2018)
FA1732, Degree course structure A.Y. 2018/19, A.Y. 2019/20
N0
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Number of ECTS credits allocated 10.0
Type of assessment Mark
Course unit English denomination ORGANIC CHEMISTRY
Department of reference Department of Pharmaceutical and Pharmacological Sciences
Mandatory attendance
Language of instruction Italian
Branch PADOVA
Single Course unit The Course unit can be attended under the option Single Course unit attendance
Optional Course unit The Course unit is available ONLY for students enrolled in PHARMACY (Ord. 2018)

Lecturers
Teacher in charge FEDERICO RASTRELLI CHIM/06

ECTS: details
Type Scientific-Disciplinary Sector Credits allocated
Basic courses CHIM/06 Organic Chemistry 10.0

Course unit organization
Period Second semester
Year 1st Year
Teaching method frontal

Type of hours Credits Teaching
hours
Hours of
Individual study
Shifts
Practice 2.0 24 26.0 2
Lecture 8.0 64 136.0 No turn

Calendar
Start of activities 02/03/2020
End of activities 12/06/2020
Show course schedule 2019/20 Reg.2018 course timetable

Examination board
Board From To Members of the board
8 Commissione a.a. 2019/20 02/12/2019 30/09/2020 RASTRELLI FEDERICO (Presidente)
GABRIELLI LUCA (Membro Effettivo)

Syllabus
Prerequisites: General and inorganic chemistry.
Target skills and knowledge: • knowing and understanding the fundamental principles of organic chemistry represented by the chemistry of monofunctional groups and their interactions in some classes of molecules of biological interest;
• knowing the specific language of organic chemistry in terms of the representation of molecules, the attribution of the rational and current name, of the reactions and their mechanisms;
• knowing the reactivity, the main synthetic methods and the mechanisms by which organic compounds are formed and transformed;
• knowing the structure-reactivity relationships, also with reference to the stereochemical aspects;
• knowing how to classify a molecule based on its functional groups;
• knowing how to attribute the rational name and possible current to the molecule and vice versa;
• knowing how to predict the physico-chemical characteristics of a compound based on its molecular structure;
• knowing how to predict its reactivity and the possible ways of its synthesis;
• applying the knowledge acquired on the chemistry of organic molecules to the solution of problems both in the strictly chemical field and in the broader context of the life sciences (with particular reference to those concerning pharmaceutical chemistry, biochemistry and pharmacology).
Examination methods: Written examination consisting of different types of questions, namely multiple choice quizzes and open quiestions with preassigned score.

The final grade is a (weighted) average on the different tests.

A pass in the multiple choice part is a necessary (but not sufficient) requirement to pass the exam.
Assessment criteria: The evaluation of the tests will take into consideration:

• the knowledge of both the IUPAC and the current nomenclature;
• the correct representation of the molecule in its electronic and steric structure (conformation, carbon configuration, optical activity)
• the ability to recognize the functional groups and their physico-chemical properties and reactivity;
• the ability to choose reagents to obtain specific products;
• the ability to propose the salient mechanisms and stereochemical aspects of some synthetic reactions;
Course unit contents: 1) Covalent bond and molecular geometry
2) Representation of organic molecules, reactions and their mechanisms
3) IUPAC and current nomenclature of molecules
4) Alkanes and cycloalkanes: radical reactions
5) Stereoisomerism and chirality
6) Alkenes: electrophilic addition reactions
7) Alkynes: acidity, electrophilic addition reactions, keto-enol tautomerism.
9) Benzene and aromatic hydrocarbons
10) Reactions of benzene, benzene derivatives and aromatic two- and three-ring aromatic hydrocarbons
11) Halo-alkanes: aliphatic nucleophilic substitution and beta-elimination
12) Organometallic compounds
13) Alcohols and phenols
14) Ethers, epoxides and sulfides
15) Amines
16) Acids and bases: evaluation criteria based on the electronic structure
17) Aldehydes and ketones: structure and reactivity. Condensation reactions.
18) Carboxylic acids: acidity and electronic structure
19) Functional carboxylic acid derivatives: nucleophilic acyl substitution and acidity in alpha derivatives
20) Carbonic acid, cyanic acid, isocyanic acid and derivatives; phosphoric acid and derivatives
21) Enolate enolate and enamines. Synthesis and properties of alpha-beta-unsaturated carbonyl compounds
22) Properties and synthesis of betachetoesters, beta carboxes esters and their use in the synthesis of ketones, acids, heterocyclic compounds
23) Aromatic heterocyclic compounds with five and six atoms
25) Carbohydrates, Lipids, Amino acids and proteins, Nucleic acids: structure, nomenclature, physico-chemical properties, reactivity.
Planned learning activities and teaching methods: Lectures, exercises and examples.
Additional notes about suggested reading: • Use of the e-learning platform
• Lecture notes
• Indications of materials available on the Internet
• Various recommended texts available in the DSF Library
Textbooks (and optional supplementary readings)
  • Brown W.H., Iverson, B.L., Anslyn E.V., Foote C.S, Chimica Organica, V ed.. Napoli: EDISES, 2015. Il testo permette l'accesso all'edizione elettronica con approfondimenti dedicati. Allegato al testo una scatola di modelli molecolari Cerca nel catalogo
  • McMurry, John; Causin, Valerio, Chimica organicaJohn McMurry. Padova: Piccin, 2017. Cerca nel catalogo