First cycle
degree courses
Second cycle
degree courses
Single cycle
degree courses
School of Science
BIOLOGY
Course unit
GENETICS (MOD. A)
SCP4068095, A.A. 2019/20

Information concerning the students who enrolled in A.Y. 2018/19

Information on the course unit
Degree course First cycle degree in
BIOLOGY
SC1165, Degree course structure A.Y. 2008/09, A.Y. 2019/20
N0
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Number of ECTS credits allocated 7.0
Type of assessment Mark
Course unit English denomination GENETICS (MOD. A)
Website of the academic structure http://biologia.scienze.unipd.it/2019/laurea
Department of reference Department of Biology
E-Learning website https://elearning.unipd.it/biologia/course/view.php?idnumber=2019-SC1165-000ZZ-2018-SCP4068095-N0
Mandatory attendance
Language of instruction English, Italian
Branch PADOVA

Lecturers
Teacher in charge MAURO AGOSTINO ZORDAN BIO/18

Integrated course for this unit
Course unit code Course unit name Teacher in charge
SCP4068094 MOLECULAR BIOLOGY AND GENETICS (I.C.) MAURO AGOSTINO ZORDAN

ECTS: details
Type Scientific-Disciplinary Sector Credits allocated
Core courses BIO/18 Genetics 7.0

Course unit organization
Period First semester
Year 2nd Year
Teaching method frontal

Type of hours Credits Teaching
hours
Hours of
Individual study
Shifts
Practice 1.0 16 9.0 No turn
Lecture 6.0 48 102.0 No turn

Calendar
Start of activities 30/09/2019
End of activities 18/01/2020
Show course schedule 2019/20 Reg.2008 course timetable

Examination board
Examination board not defined

Syllabus

Common characteristics of the Integrated Course unit

Prerequisites: Biochemistry Cell Biology
Target skills and knowledge: The students should understand the relationship between organization and function of the molecules such as nucleic acids and protein inside the cell. The course will provide the basic elements to analyze genome expression using molecular genetics tools.
Examination methods: oral or written with open questions and or multiple choice
Assessment criteria: Acquisition of a specific and appropriate language on the proposed field.
Understanding the levels of regulation of genome expression in bacterial and eukaryotic cells

Specific characteristics of the Module

Course unit contents: Course content:
1. Generalities: the aim and language of Genetics; genes and environment; genotype and phenotype.
2. Mendelian analysis: Mendel's experiments; basic human mendelian genetics.
3. Chromosomal theory of heredity: mitosis and meiosis; sex-linked heredity; parallel behaviour of autosomal genes and chromosomes; mendelian genetics and life cycles;
4. Extensions of mendelian analysis: variability in dominance relationships; multiple alleles; polygenic characters; penetrance and expressivity.
5. Chromosomal mappping in Eucaryotes: interchromosomal and intrachromosomal recombination; association maps; three-point test-cross; the chi-square test; ordered and unordered tetrad analysis; mitotic segregation and recombination.
6. The extranuclear genome: cytoplasmic heredity; mitochondrial and chloroplast genomes;
7. Structure and function of DNA and RNA: replication, transcription, translation, genetic code.
8. Chromosomal mutations: changes in the structure and/or the number.
9. Bacterial and phage genetics: recombination in bacteria and in their viruses; bacterial conjugation; bacterial recombination and mapping of the E.coli chromosome; generalized and specialized transduction in bacteriophages.
10. Nature of the gene: how genes work; fine structure of the gene; complementation.
11. Gene mutations: molecular basis of mutations; spontaneous and induced mutations; reversion analysis; relationship between mutagens and carcinogens; biological mechanisms of DNA repair.
12. Control of gene expression in Procaryotes and in Eucaryotes.
Planned learning activities and teaching methods: Frontal lessons will be alternated by excercises illustrating the solution to numerical problems in Genetics.
Additional notes about suggested reading: In addition to the suggested text books, material such as slides and/or pdf files will be provided through the Moodle platform. Through the same platform, links to web sites of genetic interest (i.e. databases dealing with model organisms mentioned during lessons) will also be provided.
Textbooks (and optional supplementary readings)
  • Robert J. Brooker, Principi di Genetica. --: McGraw-Hill, 2010. Cerca nel catalogo
  • Anthony J.F. Griffiths et al., Genetica (Settima edizione italiana condotta sulla decima edizione americana). Bologna: Zanichelli, 2013. Cerca nel catalogo
  • D. Peter Snustad & Michael J. Simmons, Principi di Genetica (Quinta edizione italiana). Napoli: Edises, 2014. Cerca nel catalogo

Innovative teaching methods: Teaching and learning strategies
  • Lecturing
  • Problem based learning
  • Interactive lecturing
  • Questioning
  • Problem solving
  • Peer feedback
  • Auto correcting quizzes or tests for periodic feedback or exams
  • Loading of files and pages (web pages, Moodle, ...)

Innovative teaching methods: Software or applications used
  • Moodle (files, quizzes, workshops, ...)
  • Matlab
  • R Statistical Software