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Course unit
GENETICS
SC07103434, A.A. 2019/20
Information concerning the students who enrolled in A.Y. 2018/19
ECTS: details
Type |
Scientific-Disciplinary Sector |
Credits allocated |
Educational activities in elective or integrative disciplines |
BIO/18 |
Genetics |
6.0 |
Course unit organization
Period |
First semester |
Year |
2nd Year |
Teaching method |
frontal |
Type of hours |
Credits |
Teaching hours |
Hours of Individual study |
Shifts |
Practice |
1.0 |
12 |
13.0 |
No turn |
Lecture |
5.0 |
40 |
85.0 |
No turn |
Examination board
Board |
From |
To |
Members of the board |
8 GENETICA 2019-2020 |
01/10/2019 |
27/11/2020 |
SANDRELLI
FEDERICA
(Presidente)
ZORDAN
MAURO AGOSTINO
(Membro Effettivo)
MAZZOTTA
GABRIELLA MARGHERITA
(Supplente)
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7 GENETICA 2018-2019 |
01/10/2018 |
30/11/2019 |
SANDRELLI
FEDERICA
(Presidente)
ZORDAN
MAURO AGOSTINO
(Membro Effettivo)
MAZZOTTA
GABRIELLA MARGHERITA
(Supplente)
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Prerequisites:
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Principles of Cell Biology |
Target skills and knowledge:
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Principles of formal and molecular genetics, basic knowledge on the structure and function of genes and on their interactions . Acquisition of the basic knowledge on the genetic structure of populations. |
Examination methods:
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The exam is a written test with three exercises of formal genetics and one open-ended question. |
Assessment criteria:
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We will evaluate the ability to solve problems of formal and population genetics and to discuss about genetic aspects , with particular attention to the correct use of terminology , definitions and concepts. |
Course unit contents:
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Introduction to Genetics: The main discoveries of the genetic research. The main branches of Genetics : formal, molecular, population . Genome structure of phages, Prokaryotes and Eukaryotes . Cell division and gene transfer in Prokaryotes . Cell Division in Eukaryotes : mitosis and meiosis (0.5 CFU).
Formal genetics : definition of genotype , phenotype and norm of reaction; Mendelian inheritance , transmission of autosomal and sex-linked characters. Formal genetic mechanisms at the molecular level. Extending Mendelian inheritance : multiple alleles , lethal alleles , interaction among genes. Pleotropy, penetrance and expressivity . Complementation and allelism test for new mutations (2 CFU).
Association and recombination. Genetic Mapping in Eukaryotes : two- and three-point mapping with genetic markers. Coefficient of coincidence and interference . Advanced genetic mapping in Eukaryotes : analysis in humans (1 CFU).
Structure and function of the genetic material: Key experiments and model of DNA replication in Prokaryotes and in Eukaryotes. Unique and repetitive sequences in the genomes. Introduction to DNA sequencing techniques (0.5 CFU).
Gene mutation and repair mechanisms ; structural and numerical chromosomal mutations (1 CFU).
Population genetics : the genetic structure of populations , the Hardy -Weinberg equilibrium , Modification in the genetic structure of populations : mutation , migration, genetic drift and selection. Population genetics in humans : some examples (1 CFU). |
Planned learning activities and teaching methods:
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The course includes 40 hours of frontal lecturing and 12 hours of exercises, regarding the application of the basic principles of Mendelian and Population genetics. The exercises will be provided to the students in advance and will be discussed during the dedicated hours. |
Additional notes about suggested reading:
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The material used during the frontal lecturing will be made available on the e-learning platform. |
Textbooks (and optional supplementary readings) |
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Russell, Genetica, Un approccio molecolare. --: Pearson, 2014.
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Binelli e Ghisotti, Genetica. --: Edises, 2017.
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Klug, Cummings, Spencer, Concept of genetics. --: Pearson, 2014.
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Innovative teaching methods: Teaching and learning strategies
- Lecturing
- Problem based learning
- Case study
- Interactive lecturing
- Working in group
- Questioning
- Problem solving
- Active quizzes for Concept Verification Tests and class discussions
- Use of online videos
- Loading of files and pages (web pages, Moodle, ...)
Innovative teaching methods: Software or applications used
- Moodle (files, quizzes, workshops, ...)
- Kahoot
Sustainable Development Goals (SDGs)
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