First cycle
degree courses
Second cycle
degree courses
Single cycle
degree courses
School of Agricultural Sciences and Veterinary Medicine
ANIMAL CARE
Course unit
GENERAL CONCEPTS IN PHARMACO-TOXICOLOGY
AVP7077493, A.A. 2019/20

Information concerning the students who enrolled in A.Y. 2018/19

Information on the course unit
Degree course First cycle degree in
ANIMAL CARE
AV2378, Degree course structure A.Y. 2017/18, A.Y. 2019/20
N0
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Degree course track Common track
Number of ECTS credits allocated 8.0
Type of assessment Mark
Course unit English denomination GENERAL CONCEPTS IN PHARMACO-TOXICOLOGY
Website of the academic structure https://www.agrariamedicinaveterinaria.unipd.it/
Department of reference Department of Comparative Biomedicine and Food Science
E-Learning website https://elearning.unipd.it/scuolaamv/
Mandatory attendance
Language of instruction English
Branch LEGNARO (PD)
Single Course unit The Course unit can be attended under the option Single Course unit attendance
Optional Course unit The Course unit can be chosen as Optional Course unit

Lecturers
Teacher in charge MAURO DACASTO VET/07
Other lecturers GIULIA MARIA DE BENEDICTIS VET/09
MARIANNA PAULETTO VET/07

ECTS: details
Type Scientific-Disciplinary Sector Credits allocated
Core courses VET/07 Veterinary Pharmacology and Toxicology 6.0
Core courses VET/09 Clinical Veterinary Surgery 2.0

Course unit organization
Period Second semester
Year 2nd Year
Teaching method frontal

Type of hours Credits Teaching
hours
Hours of
Individual study
Shifts
Practice 1.0 8 17.0 2
Lecture 7.0 56 119.0 No turn

Calendar
Start of activities 02/03/2020
End of activities 12/06/2020
Show course schedule 2019/20 Reg.2017 course timetable

Examination board
Board From To Members of the board
2 Commissione a.a. 2019/20 01/12/2019 30/11/2020 DACASTO MAURO (Presidente)
PAULETTO MARIANNA (Membro Effettivo)
DE BENEDICTIS GIULIA MARIA (Supplente)
1 Commissione a.a. 2018/19 01/12/2018 30/11/2019 DACASTO MAURO (Presidente)
DE BENEDICTIS GIULIA MARIA (Membro Effettivo)
PAULETTO MARIANNA (Supplente)

Syllabus
Prerequisites: Knowledge of biology, genetics, biochemistry and physiology.
Target skills and knowledge: Knowledge of fundamental pharmaco-toxicology, main classes of drugs and toxic substances of interest for the Bachelor in Animal Care.

Provide students basic concepts on anesthesiology, equipment for anesthesia and monitoring, perioperative management, anesthetic emergency management and cardiopulmonary resuscitation.
Examination methods: Written exam, consisting in sixty (60) multiple choice questions (MCQs, 2 points each).
Assessment criteria: The criteria for student evaluation include the degree of knowledge about specific arguments; understanding and assimilation of the topics covered in class.
Course unit contents: Course introduction

BASIC PHARMACOLOGY AND TOXICOLOGY (3 UFC)
General concepts in pharmaco-toxicology, routes of administration/exposure (including simplified operating procedures for intravenous, parenteral and topical drug administration); pharmacokinetics (absorption, distribution, metabolism and excretion); pharmacodynamics (i.e., xenobiotic-receptor interaction and mechanisms of action); factors modulating drug/xenobiotic efficacy/toxicity (species, sex, breed/strain, age, individual susceptibility), including drug-drug interactions; toxic effects, bioactivation, general concepts of toxicodynamics (e.g., oxidative stress, covalent binding to macromolecules) and factors modulating xenobiotic toxicity (e.g., DNA repair mechanisms, antioxidant enzymes); environmental toxicology, biomonitoring and biomarkers.

SPECIAL PHARMACOLOGY AND TOXICOLOGY (2 UFC)
Basic knowledge about the main classes of drugs and toxic substances of interest for the Bachelor in Animal Care. In particular: drugs acting on the autonomic and central nervous system; behavioral pharmacology; corticosteroids and non steroidal antinflammatory drugs (NSAIDs); diuretics and rehydration solutions; drugs acting on the respiratory system and gastrointestinal tract; antimicrobial chemotherapy, chemotherapy of parasitic diseases; antiseptics and disinfectants; pharmacy; basic regulatory considerations; environmental contaminants; heavy metals; herbicides; fungicides; insecticides; natural toxins, including mycotoxins.

LABORATORY OF PHARMACOLOGY AND TOXICOLOGY (1 UFC)
Exercises in pharmacology; pharmacokinetic problems; insecticides modulation of serum acetylcholinesterase enzymatic activity;
critical reading of an article of pharmacology or toxicology; ELISA (e.g., total serum proteins, beta-2 microglobulin, or aflatoxin B1).

CONCEPTS OF GENERAL ANESTHESIOLOGY (2 UFC)
General concepts in anaesthesiology (e.g., meaning of tranquilization, sedation and anaesthesia; how sedation and anaesthesia interfere with the animals’ homeostasis).
Basic information on the effects of anaesthetic drugs (tranquilizers, sedatives, ipnotic agent, cyclohexylamine, inhalant anaesthetics). Administration of anaesthetic drugs: how and when. Practical calculation in anaesthesia. Equipment used in anaesthesia. Endotracheal intubation. Patient’s monitoring. Pain management and suffering reduction. Severity classification of the experimental procedures. Safe handling and restraint. Complications, emergency, and CPR.
Practical examples, videos and interactive discussion of clinical cases will involve the student during each lecture.
Planned learning activities and teaching methods: The course includes fifty-six hours of lectures and eight hours of practicals and hands on teaching, to strengthen concepts and principles discussed in lecture sessions.
Additional notes about suggested reading: Microsoft Power Point slide presentations (PDF format) will be available on Moodle platform (https://elearning.unipd.it/scuolaamv/).
Textbooks (and optional supplementary readings)
  • Ramesh C. Gupta (Ed.), Veterinary Toxicology, Basic and Clinical Principles (2nd edition);. --: Academic Press, 2012. eBook ISBN: 9780123859273 Hardcover ISBN: 9780123859266
  • James Ritter, Rod Flower, Graeme Henderson, Humphrey Rang (Eds.), Rang & Dale’ Pharmacology (8th edition);. --: Churchill Livingstone, 2015. Paperback ISBN: 9780702053627 eBook ISBN: 9780702067020
  • John Thomas, Phillip Lerche, Anesthesia and Analgesia for Veterinary Technicians, (4th edition). --: Mosby, 2010. ISBN-10: 0323055044; ISBN-13: 978-0323055048
  • Wanamaker B., Massey K., Applied Pharmacology for Veterinary Technicians (5th edition). --: Saunders, 2014. Paperback ISBN: 9780323186629; eBook ISBN: 9780323291705

Innovative teaching methods: Teaching and learning strategies
  • Lecturing
  • Laboratory
  • Case study
  • Learning journal

Innovative teaching methods: Software or applications used
  • Moodle (files, quizzes, workshops, ...)

Sustainable Development Goals (SDGs)
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