First cycle
degree courses
Second cycle
degree courses
Single cycle
degree courses
School of Science
INDUSTRIAL BIOTECHNOLOGY
Course unit
ENVIRONMENTAL CHEMISTRY AND GENETIC TOXICOLOGY
SCN1037598, A.A. 2018/19

Information concerning the students who enrolled in A.Y. 2018/19

Information on the course unit
Degree course Second cycle degree in
INDUSTRIAL BIOTECHNOLOGY
SC1731, Degree course structure A.Y. 2014/15, A.Y. 2018/19
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Number of ECTS credits allocated 8.0
Type of assessment Mark
Course unit English denomination ENVIRONMENTAL CHEMISTRY AND GENETIC TOXICOLOGY
Website of the academic structure http://biotecnologie.scienze.unipd.it/2018/laurea_magistrale
Department of reference Department of Biology
Mandatory attendance
Language of instruction English
Branch PADOVA
Single Course unit The Course unit can be attended under the option Single Course unit attendance
Optional Course unit The Course unit can be chosen as Optional Course unit

Lecturers
Teacher in charge PAOLA VENIER BIO/19
Other lecturers SILVIA GROSS CHIM/03

ECTS: details
Type Scientific-Disciplinary Sector Credits allocated
Educational activities in elective or integrative disciplines CHIM/03 General and Inorganic Chemistry 4.0
Core courses BIO/18 Genetics 4.0

Course unit organization
Period Second semester
Year 1st Year
Teaching method frontal

Type of hours Credits Teaching
hours
Hours of
Individual study
Shifts
Laboratory 1.0 16 9.0 No turn
Lecture 7.0 56 119.0 No turn

Calendar
Start of activities 25/02/2019
End of activities 14/06/2019

Examination board
Board From To Members of the board
7 TOSSICOLOGIA AMBIENTALE: ASPETTI CHIMICI, GENETICI E GENOMICI 2018-2019 01/10/2018 30/11/2019 VENIER PAOLA (Presidente)
GROSS SILVIA (Membro Effettivo)
LAVEDER PAOLO (Supplente)
6 TOSSICOLOGIA AMBIENTALE: ASPETTI CHIMICI, GENETICI E GENOMICI 2017/2018 01/10/2017 25/11/2018 VENIER PAOLA (Presidente)
GROSS SILVIA (Membro Effettivo)
LAVEDER PAOLO (Supplente)

Syllabus
Prerequisites: Essentials of general, inorganic and organic Chemistry, Biology and Genetics
Target skills and knowledge: The course aims at providing knowledge on chemical processes and reactions involved in the action of pollutants in different environmental compartments, the variety of toxic agents and their possible effects at different levels of biological organization. This will enable students to acquire working knowledge rooted on 1) principles of environmental chemistry and toxicology, 2) natural and man-made toxic agents, 3) toxicity mechanisms, with special attention to structural and functional changes of the genetic material, 4) end-points and test systems for detecting exposure and toxicant-induced responses in humans and other organisms. Following an inter-disciplinary approach, students are expected to improve the document search and a critical view on problems related to toxic agents.
Examination methods: The exam will be a verbal interview on Part A (CHIM, 4 CFU) and Part B (BIO, 4 CFU). For Part B, the student will also debate a topic (toxic agent, biological process in terms of function/ dysfunction, investigation method) agreed with the professor during the course and based on the scientific literature. Effective reporting of biotechnological aspects will be positively evaluated.
Assessment criteria: The exam will assess 1) understanding and learning of general concepts and specific course subjects, 2) search ability and critical thinking on facts and hypothesis related to toxic agents, 3) correct use of terms and verbal efficacy, 4) positive interactions during the course.
Course unit contents: The following contents will be expanded or reduced according to the student’s skills and interest.
Part A (CHIM).
Introduction to the environmental chemistry and geobiochemical cycles. Evaluation of the pollutant distribution and transfer in the atmosphere, hydrosphere and lithosphere (0.5 CFU).
Radioactivity: principles and chemistry of radiations; ionizing and non-ionizing radiations. Types of radioactive decay (1 CFU). Atmosphere: chemistry and atmospheric pollutants; photochemical smog; role of chemical substances in the ozone layer depletion; greenhouse effect; inorganic gaseous pollutants; organic pollutants, particulates (1 CFU).
Hydrosphere: chemico-physical properties of water and water-based ecosystems; features, transport and chemical behaviour of inorganic and inorganic pollutants; contamination of natural waters; 'heavy' metals and their transport; colloids (1 CFU)
Lithosphere: soil composition and chemistry with special attention to pesticides, herbicides and 'heavy' metals (0.5 CFU).
Part B (BIO).
Variety of toxic agents and possible adverse effects at different levels of biological organization. Toxicokinetics and toxicodynamics (hints). Biological targets, measures of exposure, effect and susceptibility. Dose-response with/without threshold, hormesis. Hazard, risk, harm. Safety/precautionary symbols and regulations. Criteria for the identification of toxic agents and their characterization with traditional and innovative methods (1.5 CFU).
Effects and responses induced by non-ionizing and ionizing radiations. Dose units. Adaptive response, bystander effect, radio-resistance in cancer cells and in extremophilic bacteria (1 CFU). Genetic activity profiles, examples of the action mode of toxic chemicals (0.5 CFU). Practical experience in laboratory (1 CFU).
Planned learning activities and teaching methods: Interactive development of the course topics; use of scientific papers, toxicological databases and other web resources; practical experience in laboratory (potentially, seminars or external visits on specific subjects).
Additional notes about suggested reading: Toxicology books, scientific journals, lecture files as a study guide.
Textbooks (and optional supplementary readings)
  • S. E. Mahan, Environmental Chemistry. Boca Raton: CRC Press, 2009. 9th Edition Cerca nel catalogo
  • C. Klaassen, Casarett and Doull's Toxicology: the basic science of poisons. New York: McGraw Hill, 2013. 8th Edition, printed or electronic version Cerca nel catalogo

Innovative teaching methods: Teaching and learning strategies
  • Laboratory
  • Case study
  • Interactive lecturing
  • Working in group
  • Questioning

Sustainable Development Goals (SDGs)
Good Health and Well-Being Industry, Innovation and Infrastructure Responsible Consumption and Production