First cycle
degree courses
Second cycle
degree courses
Single cycle
degree courses
School of Medicine
Course unit
MEL1000388, A.A. 2019/20

Information concerning the students who enrolled in A.Y. 2018/19

Information on the course unit
Degree course 5 years single cycle degree in
PHARMACY (Ord. 2018)
FA1732, Degree course structure A.Y. 2018/19, A.Y. 2019/20
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Number of ECTS credits allocated 10.0
Type of assessment Mark
Course unit English denomination HUMAN PHYSIOLOGY
Department of reference Department of Pharmaceutical and Pharmacological Sciences
Mandatory attendance No
Language of instruction Italian
Single Course unit The Course unit can be attended under the option Single Course unit attendance
Optional Course unit The Course unit can be chosen as Optional Course unit

Teacher in charge ARAM MEGIGHIAN BIO/09

ECTS: details
Type Scientific-Disciplinary Sector Credits allocated
Basic courses BIO/09 Physiology 10.0

Course unit organization
Period Second semester
Year 2nd Year
Teaching method frontal

Type of hours Credits Teaching
Hours of
Individual study
Lecture 10.0 80 170.0 No turn

Start of activities 02/03/2020
End of activities 12/06/2020
Show course schedule 2019/20 Reg.2018 course timetable

Prerequisites: Students will acquire specific knowledge of the function of human body from the cell to the entire organism.
Fundamental prerequisite for understanding the arguments of the Course of Physiology is an adequate knowledge of:
Chemistry and Biochemistry
Human Anatomy
Target skills and knowledge: Students will understand the functional mechanisms regulating cell, organ and entire organism adaptive responses to changes in the internal/external environment.
The understanding of these adaptive mechanisms requires the acquisition of an unitary view of the organism as a whole rather than a knowledge based on the simple addition of specific informations about the single regulatory mechanisms.
The course will also require the student to acquire a quantitative attitude to discuss and criticize the relationship between the different biological variables involved in the homeostatic regulatory mechanisms.
The aim of the course is to give the students an adequate background useful to understand and discuss:
the basic mechanisms of disease
the functional action of different classes of drugs
how different drugs are adsorbed, transported and eliminated from the organisms
Final exam is subdivided in 5 parts. In the first part there are 30 quizzes . Evaluation: correct answer = 1 pt; incorrect, incomplete or blank answer = 0 pt. Parts 2-5 are 15 lines essays. Evaluation: each one scores max 30 pts (12 or 16 = negative; 18-30 = positive).
Final score is the average of the obtained scores. Final score is positive if the average score is equal or > to 18. Scores < to 18 are negative. In case of 3 negative scores of 5, exam is also negative.
In each official exam session (summer, fall and winter sessions) there are 2 exams (6 total).
Exam evaluations are published online on UNIWEB site
Assessment criteria: Final evaluation will test student ability to understand the single homeostatic regulatory mechanisms of our organisms, with a particular attention to exploit the capacity to integrate them into a unitary vision of our organism and to analyse them from a quantitative point of view.
Course unit contents: Homeostasis. Cell excitability: the electrical properties of cell membrane. Local potential and action potential. Action potential conduction velocity. Ionic channels. Sensory receptors. Synaptic function: synapse, neurotransmitters, post-synaptic potentials, synpatic integration. Skeletal, cardiac and smooth muscle. Heart as pump. Circulation and vessels. Capillary exchange. Systemic and local blood fluxes. Blood. Haemostasis and coagulation. Kidney: glomerular and tubular functions. Regulation of ECF osmolarity and volume; pH control; regulation of ionic concentrations (Calcium, Sodium, Potassium); secretion of urea and catabolites. Bladder function. Autonomic nervous system and its divisions. Cardiovascular regulatory mechanisms: local regulatory mechanisms, systemic regulatory mechanisms. Cardiac output regulation. Venous circulation and its regulation. Gastrointestinal function: motility, secretions, digestion and absorbption. Defecation. Diet: basal metabolism, energy metabolism; respiratory quotient; diet and exercise. Respiratory function: mechanics of respiration, pressures, volumes, respiratory muscles. Gas exchange in the lungs. Pulmunary circulation. Ventilation/perfusion quotient. Gas transport between lungs and tissues. Regulation of respiration. Endocrine system: general organization. Hormones of the anterior and posterior pituitary gland. Thyroid and Adrenal gland. Gonads. Pregnancy and its control. Pancreas. Parathyroid glands. Sensory function of the nervous system: introduction. Sensation and perception. Sensory receptors and receptor potential. Sensory modality, intensity, spatial and temporal discrimination, threshold, receptive field, lateral inhibition, adaptation. Estero- and proprio-ception. Coenesthesia. Sensory cortex. Pain. Hearing and equilibrium. Vision. Taste and smell. Hyopthalamus and limbic system.Temperature regulation. Hunger and thirst. Control of reproductive system and sexual behavior. Fear and rage. Motivation. Emotions. Motor function of the nervous system. movement and muscle tone. Reflexes, automatic movements, voluntary movement. Posture and brainstem motor systems. Motor cortex. Basal ganglia. Cerebellum. Learning and memory. Molecular mechanisms of learning and memory. Circadian clock. Associative cortex: agnosia and aphasia.

Planned learning activities and teaching methods: Physiology course consists in 9 CFU lectures (one semester) which discuss the main arguments of the program.
During lectures students are strongly stimulated to critically discuss data.
Based on students request it is possible to organize practical lectures on ECG and blood pressure measurement at rest and during and after physical exercise.
Additional notes about suggested reading: Students can download lecture powerpoint files or the complete Course Program, and have informations about suggested readings in the Course website (SELECT PROF. MEGIGHIAN AND THEN "FISIOLOGIA PER FARMACIA")
Textbooks (and optional supplementary readings)
  • CARBONE EMILIO, AICARDI GIORGIO, CICIRATA FEDERICO, Fisiologia : dalle molecole ai sistemi integrati. NAPOLI: EDISES, 2008. Testo di consultazione Cerca nel catalogo
  • SHERWOOD LAURALEE, Fondamenti di fisiologia umana. PADOVA: PICCIN, 2012. Testo consigliato Cerca nel catalogo

Innovative teaching methods: Teaching and learning strategies
  • Lecturing
  • Problem based learning
  • Case study
  • Questioning

Innovative teaching methods: Software or applications used
  • Moodle (files, quizzes, workshops, ...)

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