First cycle
degree courses
Second cycle
degree courses
Single cycle
degree courses
School of Science
Course unit
SC06100878, A.A. 2018/19

Information concerning the students who enrolled in A.Y. 2017/18

Information on the course unit
Degree course First cycle degree in
SC1165, Degree course structure A.Y. 2008/09, A.Y. 2018/19
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Number of ECTS credits allocated 7.0
Type of assessment Mark
Course unit English denomination CELLS BIOLOGY
Website of the academic structure
Department of reference Department of Biology
E-Learning website
Mandatory attendance
Language of instruction Italian
Single Course unit The Course unit can be attended under the option Single Course unit attendance
Optional Course unit The Course unit can be chosen as Optional Course unit

Teacher in charge FRANCESCA CIMA BIO/06
Other lecturers GIORGIA BEFFAGNA MED/46

ECTS: details
Type Scientific-Disciplinary Sector Credits allocated
Basic courses BIO/01 General Botanics 1.0
Basic courses BIO/06 Comparative Anatomy and Citology 6.0

Course unit organization
Period First semester
Year 2nd Year
Teaching method frontal

Type of hours Credits Teaching
Hours of
Individual study
Laboratory 2.0 32 18.0 2
Lecture 5.0 40 85.0 No turn

Start of activities 01/10/2018
End of activities 18/01/2019
Show course schedule 2019/20 Reg.2008 course timetable

Examination board
Board From To Members of the board
8 BIOLOGIA CELLULARE 2019-2020 01/10/2019 27/11/2020 CIMA FRANCESCA (Presidente)
BALLARIN LORIANO (Membro Effettivo)
MANNI LUCIA (Supplente)
7 BIOLOGIA CELLULARE 2018-2019 01/10/2018 30/11/2019 CIMA FRANCESCA (Presidente)
BALLARIN LORIANO (Membro Effettivo)
MANNI LUCIA (Supplente)
6 BIOLOGIA CELLULARE 2017/2018 01/10/2017 25/11/2018 CIMA FRANCESCA (Presidente)
BALLARIN LORIANO (Membro Effettivo)
MANNI LUCIA (Supplente)

Prerequisites: The course requires knowledge of Foundamental of Biology and Biochemistry.
Target skills and knowledge: The continuous succession of advances and discoveries in Molecular and Cell Biology require the need to offer an integrated view and a large amount of synthetic knowledge that in few decades have largely developed and continue to evolve. Therefore, since students are continuously stimulated by both personal experiences and media they must be guided to understand and know properly many aspects of biological structures, life phenomena, and cell-cell and cell-environment interactions

The course aims to highlight the following knowledge:
1) the organization of cells even in light of the evolutionary processes which have led to the emergence of prokaryotes and eukaryotes and various structural organizations among eukaryotes;
2) the cell structures, the main phenotypic features, functional interactions, communication ways, and the different mechanisms by which the cell organises its molecular structures, uses and transforms the energy substances, reproduces itself with a continuous stream of information, regulates its life and death.
3) in laboratory applications, the characteristics and use of various types of microscope, the observation of cell structures in the various types of tissues and learning some classical histological techniques will be considered and learnt.

As for skills and competences that students will gain, the aims of the course is
1) to help to create in students a critical attitude, analysis and synthesis;
2) to learn to recognize the unifying trend of scientific thought, and then look for the close links between the various concepts;
3) to promote research and encourage the acquisition of a personal study method;
4) to develop communication skills with a scientifically correct language; 6) to develop recognition capabilities of histological microslides and use histological methods.
Examination methods: Two-part written examination not to be taken separately.
1) Cell Biology: test with 25 single and multiple-choice questions on all the main topics (see Contenuti – Contents of lessons) (5 CFU)
2) Histology: test with 10 single and multiple-choice questions, and recognition with description of three histological microslides (v. Contenuti – Contents of applications and laboratory exercises) (2 CFU).
Assessment criteria: Each part of the written examination will undergo a specific evaluation and will be both positive (the min score of each part must be 18/30). Wrong answers or not given ones. For multiple answers, partial validity will be considered. The absence or wrong recognition of the histological microslides and off topic descriptions will be considered invalid (score 0). In the histological descriptions, the ability to synthesize, the language and the completeness of the concepts will be evaluated. The final score will be expressed in thirtieths.
Course unit contents: Contents of lessons (5 CFU):
1) Fundamental properties of cells. Cell origin and evolution of energy metabolism. Cell theory. Prokaryotic cell. Internal organisation of the eukaryotic cell: general characteristics, size and shape, origin and evolution. (1.125 CFU)
2) Cell organization. Pluricellular condition. (0.25 CFU)
3) Cell membrane: chemical components and structure. Plasmalemma. Formation and recycling of membranes. Membrane transports.
Exocytosis and endocytosis. Membrane potentials. (0.375 CFU)
4) Cytoskeleton: organization and functions of the interactive network of protein filaments. Microtubules. Microfilaments. Cell motility. Cell-extracellular matrix interactions. Cell adhesion to the substrate. Cell adhesion with other cells. (0.625 CFU)
5) Nucleus: organization and constituents. Nucleolus. Chromatin organization. (0.25 CFU)
6) Cell reproduction. Cell division and sexuality in prokaryotes. Mitosis and meiosis. Cell cycle. Gametogenesis. (0.75 CFU)
7) Protein synthesis. Protein glycosilation. (0.375 CFU)
8) Cell communication: types of informational molecules and signal transduction pathways. (0.625 CFU)
9) Cell death. Necrosis and apoptosis. Intrinsic and extrinsic induction of apoptosis. Recognition of cells and apoptotic bodies. (0.375 CFU)
10) Immune system. (0.25 CFU)

Contents of applications and laboratory exercises (2 CFU):
1) Use of the light microscope (0.25 CFU)
2) Observation of preparations by SEM and TEM: (0125 CFU)
3) Epithelial tissues (0.25 CFU)
4) Glandular epithelial tissue (0125 CFU)
5) Connective tissues proper (0.25 CFU)
6) Special connective tissues (0.25 CFU)
7) Muscular and nervous tissues(0.25 CFU)
8) Preparation of histological samples, tissue embedding, cutting with microtome, staining, mounting and observation of histological preparations (0.25 CFU)
9) Fixation, staining and observation of cultured cells (haemocytes of marine invertebrates), use of a counting chamber (0125 CFU)
10) Review of the histological microslides (0125 CFU)
Planned learning activities and teaching methods: Lessons will be held in the classroom with the support of pdf files. The teaching material will be made available in a elearning platform. At the end of each topic, a self-assessment test will be submitted to students.

The practical laboratory exercises will include
1) knowledge of various microscopic techniques (light, fluorescence, confocal microscopes, and transmission and scanning electron microscopes),
2) visit to the main equipment of the Dept. of Biology: SEM and TEM and equipment for sample preparation (ultramicrotomes, critical point, sputtering, and so.);
3) using light microscopy for the analysis of histological structures under the guide of a tutor;
4) tpresentation of techniques and histological preparations through self-produced tutorial movies;
5) carrying out of histology and cytology preparations with different staining methods (both in vivo and fixed materials).
A self-assessment test will be submitted to students on each histological topic.
Additional notes about suggested reading: Teacher lecture notes, background material, information about examination dates will be reported in the elearning platform, accessible with a password provided by the teacher at the beginning of the course lessons. Teacher’s personalized e-book edition of Karp, Biologia Cellulare e Molecolare (EdiSES).
Textbooks (and optional supplementary readings)
  • Karp, Gerald; Patton, James G., Biologia cellulare e molecolareconcetti ed esperimenti. Napoli: EdiSES, 2015. Cerca nel catalogo
  • De_Leo, Giacomo; Ginelli, Enrico; Fasano, Silvia, Biologia e geneticaa cura di Giacomo De Leo, Silvia Fasano, Enrico Ginelli. Napoli: EdiSES, 2013. Cerca nel catalogo
  • Ciarcia, Gaetano; Cardellini, Pietro; Bonfanti, Patrizia, Citologia e istologiaBonfanti ... [et al.]coordinamento editoriale P. Cardellini e G. Ciarcia. Napoli: Idelson-Gnocchi, 2010. Cerca nel catalogo
  • Dalle_Donne, Isabella, Istologia ed elementi di anatomia microscopicaI. Dalle Donne... [et al.]. Napoli: Edises, 2011. Cerca nel catalogo
  • Calloni, Carlo; Innocenti, Riccardo, IstologiaCarlo Calloni e Riccardo Innocenti. Firenze: Giunti, 2007. Cerca nel catalogo

Innovative teaching methods: Teaching and learning strategies
  • Laboratory
  • Auto correcting quizzes or tests for periodic feedback or exams
  • Use of online videos
  • Loading of files and pages (web pages, Moodle, ...)

Innovative teaching methods: Software or applications used
  • Moodle (files, quizzes, workshops, ...)

Sustainable Development Goals (SDGs)
Life on Land