First cycle
degree courses
Second cycle
degree courses
Single cycle
degree courses
School of Agricultural Sciences and Veterinary Medicine
Course unit
MVN1027951, A.A. 2017/18

Information concerning the students who enrolled in A.Y. 2017/18

Information on the course unit
Degree course First cycle degree in
MV1734, Degree course structure A.Y. 2011/12, A.Y. 2017/18
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Number of ECTS credits allocated 11.0
Type of assessment Mark
Course unit English denomination PHYSIOLOGY AND GENERAL PATHOLOGY
Website of the academic structure
Department of reference Department of Comparative Biomedicine and Food Science
E-Learning website
Mandatory attendance No
Language of instruction Italian
Single Course unit The Course unit CANNOT be attended under the option Single Course unit attendance
Optional Course unit The Course unit is available ONLY for students enrolled in SAFETY AND HYGIENE OF FOOD PRODUCTS

Teacher in charge LUCA BARGELLONI BIO/13
Other lecturers DANIELA BERTOTTO VET/02

ECTS: details
Type Scientific-Disciplinary Sector Credits allocated
Optional VET/02 Veterinary Physiology 5.0
Optional VET/02 Veterinary Physiology 5.0
Optional VET/03 General Pathology and Veterinary Pathological Anatomy 6.0
Optional VET/03 General Pathology and Veterinary Pathological Anatomy 6.0

Course unit organization
Period Second semester
Year 1st Year
Teaching method frontal

Type of hours Credits Teaching
Hours of
Individual study
Practice 2.0 20 30.0 3
Lecture 9.0 72 153.0 No turn

Start of activities 26/02/2018
End of activities 01/06/2018
Show course schedule 2019/20 Reg.2011 course timetable

Examination board
Board From To Members of the board
9  Commissione a.a. 2018/19: dal 24/02/2019 24/02/2019 30/11/2019 GELAIN MARIA ELENA (Presidente)
BERTOTTO DANIELA (Membro Effettivo)
8  Commissione a.a. 2018/19: fino al 23/02/2019 01/12/2018 23/02/2019 BARGELLONI LUCA (Presidente)
BERTOTTO DANIELA (Membro Effettivo)
7  Commissione a.a. 2017/18 01/12/2017 30/11/2018 BARGELLONI LUCA (Presidente)
BERTOTTO DANIELA (Membro Effettivo)
6 Commissione A.A. 2016/17 01/12/2016 30/11/2017 BARGELLONI LUCA (Presidente)
BERTOTTO DANIELA (Membro Effettivo)

Prerequisites: Basic knowledge on simple and complex organisms and their biocehmical-molecular systems.
Required previous knowledge: Vewterinary Anatomy, General Chemistry and Fundaments of Bioechmistry, Animal Biology and Quantitative Genetics of Farm Animals
Target skills and knowledge: The course consists of two parts: General Pathology (6 CFUs) and Physiology (5 ECTs)

General Pathology
Basic knowledge of vertebrate immune system, with specific focus on food allergies and the role of immune system in food-related diseases. Knowldge on cellular and molecular mechanisms underlying disease and inflammation specifically for infectious and food-borne diseases.
General features of infections, host-pathogen interactions, mode of action of toxins from food-borne pathogens.
General pathology of neoplastic diseases, cellular and molecular mechanisms of tumour development.
Basics of necroscopy methods.

To understand physiology of cells, tissues and systems to maintain homeostasis in farmed species To acquire function principles and in particular those correlated with animal food production and feeding (muscle physiology, digestion and lactation).
Examination methods: Written exam with 5 questions with free text asnwer (General Pathology) and oral exam on Physiology
Assessment criteria: Evaluation of acquired knowledge on specific topics included in the course program, ability to discuss and solve specific problems, capacity to infer links within- and across-discipline, use of appropriate terminology.
Course unit contents: General Pathology

Principles of immunology (24 teaching hours)
Immune system components, Innate and acquired immunity. Antigen recognition and effector mechanisms of acquired immunity. Antibody structure. Antigen-antibody interactions. Antigen presentation. Lymphocyte receptors. Lymphocyte response to antigens. Immune tolerance. Allergy. Immunity and defense against pathogens.

Molecular basis of cell injury. Reversible and irreversible injury. Cell death. (8 teaching hours)

Inflammation and repair. Definition and generalities on inflammation and pathogenesis. Classification of inflammation types. Acute inflammation. Exudate, inflammatory cells and their functions. Chemical mediators of inflammation. Systemic effects of acute inflammation. Chronic inflammation. Granulomas. Healing: regeneration,repair, scarring, fibrosis. (5 teaching hours)

General aspects of oncology. Human and animal tumour epidemiology. Calssification criteria of neoplasia. Origin and progression of tumour development. Oncogenes and tumour-suppressor genes. Systemic effects of neoplasia: metastasis formation. Etiology of neoplasia: intrinsic and extrinsic factors. (5 teaching hours)

Necroscopic exam. (10 teaching hours)

• Principles of Cell Physiology, the Body Fluid Compartments and the Blood. (1 ECTs)
The body fluid compartments: volume, osmolarity and principle constituents. Plasma composition and properties: plasma proteins characteristics and functions. Blood cell structures in domestic species. Platelets and homeostasis. Blood sampling. sample preservation, anticoagulants.
• Physiology of excitable tissues. (1 ECTs)
Introduction to neural communication. Neurotrasmitters; physiology of muscular contraction. Nervous system organization and function.

• Endocrinology (1½ ECTs)
Hormone structure and transport. Hormone action mechanism. Hypothalamic-pituitary system. Thyroid, pancreatic, adrenal and sexual hormones. Serum calcium hormonal control. Endocrine stress response.
• Reproduction and Lactation physiology (1 ECTs)
Endocrine control of reproduction. Gonadotropins and sexual steroids. Estral cycle, ovulation, pregnancy and parturition. Lactation phases and mammary gland endocrine activity . Biosintesis of milk components and colostrum.
• Digestive physiology (1 ECTs)
Compared analysis of digestive function. Digestive system control mechanisms. Chewing, salivation, and swallow. Lumen digestion and gastric motility. swalllow. Digestive and gastric motility. Lumen and membrane digestion; absorption of nutrients. Prestomach microbiology and function. The liver.

• Kidney physiology (½ ECTs)
Glomerular filtration. proximal tubule, reabsorption, secretion. Henle loop. Ansa di Henle. Distal convoluted tubule and collecting duct system. Urine.
Planned learning activities and teaching methods: The course consists of 85 hours of theorical lectures and 10 hours of practicals (necroscopy room)
Additional notes about suggested reading: Teaching material is available on Moodle platform (
Lecture attendanceis recommended.
Visiting hours: by appointment
Textbooks (and optional supplementary readings)
  • Oystein Sjastaad, Olav Sand, Knut Hove (, Fisiologia degli animali domestici.. --: Casa Editrice Ambrosiana, 2013. ISBN: 978-88-08-18293-7
  • Robbins, Cotran, Le basi patologiche delle malattie. Patologia generale.. --: Elsevier, 2010. ISBN 8821431754 Cerca nel catalogo
  • Sherwood L., Klandorf H., Yancey P, Fisiologia degli Animali – dai geni agli organismi. --: Zanichelli, 2007. ISBN 8808070298 (testo di riferimento) Cerca nel catalogo