First cycle
degree courses
Second cycle
degree courses
Single cycle
degree courses
School of Medicine
PHARMACY
Course unit
DRUG ANALYSIS 1
MEP3051728, A.A. 2019/20

Information concerning the students who enrolled in A.Y. 2017/18

Information on the course unit
Degree course 5 years single cycle degree in
PHARMACY (Ord. 2009)
FA1732, Degree course structure A.Y. 2009/10, A.Y. 2019/20
N0
bring this page
with you
Number of ECTS credits allocated 12.0
Type of assessment Mark
Course unit English denomination DRUG ANALYSIS 1
Department of reference Department of Pharmaceutical and Pharmacological Sciences
E-Learning website https://elearning.unipd.it/dsf/course/view.php?idnumber=2019-FA1732-000ZZ-2017-MEP3051728-N0
Mandatory attendance
Language of instruction Italian
Branch PADOVA
Single Course unit The Course unit CANNOT be attended under the option Single Course unit attendance
Optional Course unit The Course unit is available ONLY for students enrolled in PHARMACY (Ord. 2009)

Lecturers
Teacher in charge CRISTINA MARZANO CHIM/08
Other lecturers MATTIA STURLESE CHIM/08

ECTS: details
Type Scientific-Disciplinary Sector Credits allocated
Core courses CHIM/08 Pharmaceutical Chemistry 12.0

Course unit organization
Period First semester
Year 3rd Year
Teaching method frontal

Type of hours Credits Teaching
hours
Hours of
Individual study
Shifts
Laboratory 4.0 60 40.0 2
Lecture 8.0 64 136.0 No turn

Calendar
Start of activities 30/09/2019
End of activities 18/01/2020
Show course schedule 2019/20 Reg.2018 course timetable

Examination board
Board From To Members of the board
9 Commissione a.a. 2019/20 02/12/2019 30/09/2020 MARZANO CRISTINA (Presidente)
STURLESE MATTIA (Membro Effettivo)

Syllabus
Prerequisites: Basic knowledge in General, Inorganic, Organic and Analytical Chemistry. Knowledge in chemical laboratory safety and security. Knowledge in basic procedures for experimental chemistry.
The student to attend the course must have attended the Course of "Laboratory preliminary to the analysis of drugs"
Target skills and knowledge: The course aims at providing basic knowledge on the subject and the abilities that are essential for a successful attendance of the laboratory practical activities. Modern instrumental methods as well as traditional chemical methods, referring to the identification of drugs reported in Pharmacopoeia will be studied. The objectives of the course are also defined in view of the preparation needed for the practical test of the State Professional Examinations enabling to work as Pharmacist.
Examination methods: The final exam consists of a written test (2 hrs long) covering the entire course program and composed of 3 open questions (0-8 points for each question) and 10 multiple-choice questions (total 0-6 points).
Assessment criteria: The assessment of learning will be done through the evaluation of the comprehension of the addressed topics and on the bases of the concepts and methodologies learnt during the class session. The ability of the student of using such aspects in an independent way will also be considered.
Course unit contents: Lectures and practicals are integrated with the view that theory can be explained in the lecture and then applied and tested in the practical laboratory work.
Lectures. Introduction to the pharmaceutical analysis. Physical properties of pharmaceutical interest (appearance, texture, color, odor, melting point, boiling point, density), Solubility and factors affecting solubility. Organic elemental analysis. Determination of carbon, hydrogen, nitrogen, sulfur, halogens and phosphorus. Chemical reactions for the recognition of functional groups in organic drugs. Specific chemical reactions according to Eur. Ph for the recognition of individual drugs (listed in the Laboratory practice book). Chromatographic methods: adsorption, distribution, ion exchange and size exclusion chromatography. Column chromatography, flat surfaces chromatography, high performance liquid chromatography (HPLC), gas chromatography.
Spectrometric methods: UV-visible, infrared, fluorescence Spectrophotometry. NMR spectrometry. Mass spectrometry. Polarimetry. Information on technics of literature search on paper and on computer databases.
The practical part of the course consists of individual exercises and/or group exercises concerning:
1. Preliminary practical lessons.
2. Identification of the chemical nature of substances.
3. General assays for the identification of main functional groups.
4. Identification of organic drugs registered in the Eur. Ph.
6. Application of instrumental techniques for separation and identification of drugs.
Planned learning activities and teaching methods: The course is organised on the basis of lectures (64 hrs) supported by PowerPoint slides and laboratory practical activities. Laboratory activities will be carried out by students individually to acquire the ability to identify a compound of pharmaceutical interest or, for some practical activities, consist of instrumental analysis carried out in small groups. All the experiments will reinforce concepts already covered in the lecture course.
Students are also followed in the laboratory by tutors and laboratory technicians.
Additional notes about suggested reading: Lecture notes. The didactic material of the course is preliminary available to the students as electronic version through the e-learning platform.
.  
Textbooks (and optional supplementary readings)
  • F.Savelli O. Bruno, Analisi Chimico Farmaceutica. Perugia: Piccin, 2005. Cerca nel catalogo
  • Dispensa parte pratica, Analisi dei Medicinali 1- Guida al Laboratorio.. --: Libreria Cortina, --.

Innovative teaching methods: Teaching and learning strategies
  • Lecturing
  • Laboratory
  • Interactive lecturing
  • Working in group
  • Questioning
  • Problem solving
  • Use of online videos

Innovative teaching methods: Software or applications used
  • Moodle (files, quizzes, workshops, ...)

Sustainable Development Goals (SDGs)
Good Health and Well-Being Quality Education