First cycle
degree courses
Second cycle
degree courses
Single cycle
degree courses
School of Agricultural Sciences and Veterinary Medicine
Course unit
AVP7079864, A.A. 2019/20

Information concerning the students who enrolled in A.Y. 2017/18

Information on the course unit
Degree course 5 years single cycle degree in
MV0991, Degree course structure A.Y. 2017/18, A.Y. 2019/20
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Number of ECTS credits allocated 6.0
Type of assessment Mark
Course unit English denomination GENERAL PATHOLOGY
Website of the academic structure
Department of reference Department of Animal Medicine, Production and Health
E-Learning website
Mandatory attendance
Language of instruction Italian
Single Course unit The Course unit CANNOT be attended under the option Single Course unit attendance
Optional Course unit The Course unit is available ONLY for students enrolled in VETERINARY MEDICINE (Ord. 2017)

Teacher in charge MASSIMO CASTAGNARO VET/03

ECTS: details
Type Scientific-Disciplinary Sector Credits allocated
Core courses VET/03 General Pathology and Veterinary Pathological Anatomy 6.0

Course unit organization
Period First semester
Year 3rd Year
Teaching method frontal

Type of hours Credits Teaching
Hours of
Individual study
Lecture 6.0 60 90.0 No turn

Start of activities 30/09/2019
End of activities 18/01/2020
Show course schedule 2019/20 Reg.2017 course timetable

Examination board
Board From To Members of the board
3 Commissione a.a. 2019/20 01/12/2019 30/11/2020 CASTAGNARO MASSIMO (Presidente)
2 Commissione a.a. 2018/19 01/12/2018 30/11/2019 CASTAGNARO MASSIMO (Presidente)

Prerequisites: Students should have reached an adequate knowledge of physiscs (in particular emphasis on fluid dynamics and physiscs of radiation), biology (DNA structure and mendelian genetics), molecular biology (control of genic expression and transcription in eucaryotic cells and cell cycle), veterinary embryology (differentiation of germ layers and stem cells), Veterinary Anatomy and Istology, Veterinary Physiology, Veterinary Parasitology and Veterinary Microbiology, Virology and Immunology. The course of Veterinary Physiology II is mandatory to pass the course of Veterinary Pathology.
Target skills and knowledge: Expected outcome of the course are adequate knowledge of causes, mechanisms and major outcome of veterinary diseases. In particular, knowledge will be focus on:
1. Cell adaptation, change and death
2. Genetic diseases
3. Vascular disorders
4. Inflammatory process and healing
5. Mechanisms of microbic infection
6. Immunopathology
7. Neoplastic processes
Examination methods: Students have to pass three mid term written tests (multiple choice and open questions). At the end of the course only students with an adequate score will seat for a final oral exam. Students that fail one of the mid term test have to seat to a final comprehensive exam. The latter can be taken by any students who did not want to take mid term exams.
Assessment criteria: Students will be assessed on the basis of their knowledge of topics presented during theoretical lectures. Criteria will be focused on the ability of the student to identify mechanisms progression of diseases from initial cause to clinical and pathological outcome.
Course unit contents: Cell injury and death
Molecular basis of cell injury. Reverible and irreverisible cell injury. Cell death.
Inflammatory healing processes
Definition, general aspects and pathogenesis of inflamamtion. Classification of inflammation. Pathogenesis of acute inflammation. Exudate formation. The cells of acute inflammation eand their functions. Chemical mediators of acute inflammation. Systemic effects of acute inflammation.
General features of chronic inflammation. Granulomatous inflammation. Healing processes: tissue regeneration, tissue repair and fibrosis.
Components of immune system. Innate and adaptive immunity. Lymphocyte activation and immune responses. Immunologic tolerance. Type I, II, III and IV hypersensitivity reactions. Autoimmunity.
Definition and general aspects of oncology. Human and animal neoplasia epidemiology. Classification criteria for neoplasia. Benign and malignant neoplasia (differentiation, proliferation and control of the cell cycle, growth type, invasion, metastases, host effects). Tumor development (clonal selection, genetic and epigenetic alterations). The hallmark of cancer. Chemical and viral carcinogenesis.
Genetic diseases
Gene mutations. Mendelian disorders. Chromosomal mutations. Multifactorial inheritance. Disorders with non classical inheritance.
Mechanisms of microbial infections
Chronological sequence of steps in microbial infections. Defensive mechanisms. Bacterial diseases. Viral diseases. Mycoses. Prion diseases.
Planned learning activities and teaching methods: Teaching activity is mainly performed with theoretical lectures. Students are requested to actively partecipate during lectures in order to develop the ability to link their knowledge to the new topic or to link different area of veterinary pathology. Some hours of lectures will be spent in the microscpoy hall to look at histologic specimens.
Additional notes about suggested reading: 1. Pathologic Basis of Veterinary Disease, J.F. Zachary, Elsevier, 6th Edition, 2016.
2. Robbins and Cotran Pathologic Basis of Disease, Kumer, Abbas, Aster, Elsevier, 9th Edition, 2015.
3. PDF files of theoretical lecturs on moodle platform (Piattaforma Moodle di Scuola)
Textbooks (and optional supplementary readings)
  • Zachary, James F., Pathologic basis of veterinary diseaseJames F. Zachary. Saint Louis: MO, Elsevier, --. Cerca nel catalogo
  • Kumar, Vinay; Abbas, Abul K.; Aster, Jon C., Robbins and Cotran pathologic basis of diseaseVinay Kumar, Abul K. Abbas, Jon C. Asterwith illustrations by James A. Perkins. Philadelphia: Elsevier, 2015. Cerca nel catalogo