First cycle
degree courses
Second cycle
degree courses
Single cycle
degree courses
School of Science
BIOTECHNOLOGY
Course unit
CELLS BIOLOGY
SCN1036885, A.A. 2016/17

Information concerning the students who enrolled in A.Y. 2016/17

Information on the course unit
Degree course First cycle degree in
BIOTECHNOLOGY
IF1839, Degree course structure A.Y. 2011/12, A.Y. 2016/17
N0
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Number of ECTS credits allocated 8.0
Type of assessment Mark
Course unit English denomination CELLS BIOLOGY
Website of the academic structure http://biotecnologie.scienze.unipd.it/2016/laurea
Department of reference Department of Biology
E-Learning website https://elearning.unipd.it/biologia/course/view.php?idnumber=2016-IF1839-000ZZ-2016-SCN1036885-N0
Mandatory attendance
Language of instruction Italian
Branch PADOVA
Single Course unit The Course unit can be attended under the option Single Course unit attendance
Optional Course unit The Course unit can be chosen as Optional Course unit

Lecturers
Teacher in charge LUISA DALLA VALLE BIO/06

ECTS: details
Type Scientific-Disciplinary Sector Credits allocated
Basic courses BIO/01 General Botanics 1.0
Core courses BIO/06 Comparative Anatomy and Citology 7.0

Course unit organization
Period First semester
Year 1st Year
Teaching method frontal

Type of hours Credits Teaching
hours
Hours of
Individual study
Shifts
Laboratory 1.0 16 9.0 No turn
Lecture 7.0 56 119.0 No turn

Calendar
Start of activities 01/10/2016
End of activities 20/01/2017
Show course schedule 2019/20 Reg.2011 course timetable

Examination board
Board From To Members of the board
11 BIOLOGIA CELLULARE 2019-2020 01/10/2019 27/11/2020 DALLA VALLE LUISA (Presidente)
PONTARIN GIOVANNA (Membro Effettivo)
RAMPAZZO CHIARA (Supplente)
10 BIOLOGIA CELLULARE 2018-2019 01/10/2018 30/11/2019 DALLA VALLE LUISA (Presidente)
PONTARIN GIOVANNA (Membro Effettivo)
RAMPAZZO CHIARA (Supplente)
8 BIOLOGIA CELLULARE 2016-2017 01/10/2016 30/11/2017 DALLA VALLE LUISA (Presidente)
PONTARIN GIOVANNA (Membro Effettivo)
RAMPAZZO CHIARA (Supplente)

Syllabus
Prerequisites: Student needs basic knowledge of chemistry, physics and biochemistry. Preliminary fundamental principles of cell biology are strongly recommended.
Target skills and knowledge: The cell biology course provides a basic understanding of cell structure, functions of organelles and cellular components, interactions between cells.
Examination methods: Written examinations will include multiple-choice questions, true/false, short and long essays.
Assessment criteria: The evaluation of the exam will consider:
the proper understanding of basic language and principles of cell biology, the ability to describe the cellular morphology and cell functions, the knowledge of the main biological macromolecules.
Course unit contents: Prokaryotic and eukaryotic cells; cell evolution in relation to the external environment. Tools and methods used in cell biology. The light microscope, fluorescence microscope; confocal microscope; the electron microscope: transmission electron microscope (TEM), scanning electron microscope (SEM). Magnification and limit of resolution.
The plasma membrane: structure of cell membrane, membrane components, phospholipid bilayers, membrane proteins and their interaction in membranes. Membrane permeability, diffusion and osmosis, facilitated and active membrane transport systems, ion channels, endocytosis and exocytosis.
Cell junctions and cell-extracellular matrix adhesion. Cell surface specializations: microvilli, cilia and flagella. Intracellular communication.
Molecular structure and function of the cytoplasmatic organelles; rought and smooth endoplasmic reticulum, Golgi apparatus, protein synthesis and ribosomes, signal sequence, protein processing in the endomembrane system; targeting of proteins to the endoplasmic reticulum; co-translational insertion of proteins in membranes; protein processing in the ER and Golgi; compartmentalization and protein sorting, vesicle formation, secretory and lysosomal pathways, endocytosis and intracellular digestion. Protein folding and degradation.
The major cytoskeletal components of cells; structure and dynamic instability of microtubules and actin filaments; microtubules in interphase and during mitosis, intermediate filaments, motor proteins, cell motility, actin and myosin interactions in muscle and non-muscle cells.
Mitochondria: molecular structure and function. Endosymbiontic origin. Mitochondrial DNA. Mitochondrial membrane. Tri-carboxylic acid cycle and the electron transport chain (brief notes).
Plant cell structure: cell wall, chloroplasts and non-photosynthetic plastids. Endosymbiontic origin. Vacuole.
The cell nucleus: nuclear envelope, pores, chromatin structure; nucleolus structure and function. Histones and nucleosomes. DNA organization: from chromatin to chromosome. Ribosomal genes organization.
The eukaryotic cell cycle: the phases of the cell cycle: checkpoint cell cycle control, activation and control of cyclin dependent kinase activity, regulation of the cell cycle, chromosomal replication, molecular mechanics of mitosis an meiosis. Cell proliferation; the programmed cell death: apoptosis and death signal transduction.
Cell communication: autocrine, paracrine, justacrine, endocrine modalities. Signal transduction: receptor channels, GPCRs and G proteins, tyrosine kinases and other receptor groups.
Embryonic and adult stem cells.
Planned learning activities and teaching methods: The course is organized with frontal lessons and laboratory sessions. The contents of frontal lessons are presented with the help of powerpoint presentations based on pictures from Cell biology textbooks or scientific articles.
Laboratory sessions (16 hours) require the direct involvement of students and are organized according to different topics:
use of microscope, cell culture preparation and analysis, mitotic index calculation, apoptotic and mitotic cells observation, cell growth curve generation.
Additional notes about suggested reading: All resources used during the course will be available on the web site https://elearning.unipd.it/cmela/.
Textbooks (and optional supplementary readings)
  • G.M. Cooper e R.E. Hausman, La cellula. Un approccio molecolare.. --: Piccin, 2012. quinta edizione Cerca nel catalogo
  • G. Karp, Biologia Cellulare e molecolare.. --: Edizioni EdiSES, 2015. quinta edizione Cerca nel catalogo
  • Wayne M. Becker - Lewis J. Kleinsmith - Jeff Hardin - Gregory Paul Bertoni, Il mondo della cellula.. --: Edizioni Pearson, 2014. settima edizione Cerca nel catalogo
  • George Plopper, Biologia della cellula.. --: Zanichelli, 2016. prima edizione Cerca nel catalogo
  • Alberts A. - Bray D. - Hopkins k. - Johnson A. - Lewis J. - Raff M. - Roberts K. - Walter P., L'essenziale di Biologia molecolare della cellula.. --: Zanichelli, 2015. quarta edizione Cerca nel catalogo