First cycle
degree courses
Second cycle
degree courses
Single cycle
degree courses
School of Science
Course unit
GENETICS (Iniziali cognome A-L)
SC11103434, A.A. 2016/17

Information concerning the students who enrolled in A.Y. 2016/17

Information on the course unit
Degree course First cycle degree in
IF1839, Degree course structure A.Y. 2011/12, A.Y. 2016/17
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Number of ECTS credits allocated 7.0
Type of assessment Mark
Course unit English denomination GENETICS
Website of the academic structure
Department of reference Department of Biology
E-Learning website
Mandatory attendance
Language of instruction Italian
Single Course unit The Course unit can be attended under the option Single Course unit attendance
Optional Course unit The Course unit can be chosen as Optional Course unit

Teacher in charge GEROLAMO LANFRANCHI BIO/18

ECTS: details
Type Scientific-Disciplinary Sector Credits allocated
Basic courses BIO/18 Genetics 7.0

Course unit organization
Period Second semester
Year 1st Year
Teaching method frontal

Type of hours Credits Teaching
Hours of
Individual study
Laboratory 1.0 16 9.0 No turn
Lecture 6.0 48 102.0 No turn

Start of activities 27/02/2017
End of activities 09/06/2017
Show course schedule 2019/20 Reg.2011 course timetable

Examination board
Board From To Members of the board
12 M-Z GENETICA 2018-2019 01/10/2018 30/11/2019 SANDRELLI FEDERICA (Presidente)
11 A-L GENETICA 2018-2019 01/10/2018 30/11/2019 LANFRANCHI GEROLAMO (Presidente)
LAVEDER PAOLO (Membro Effettivo)
10 M-Z GENETICA 2017/2018 01/10/2017 25/11/2018 SANDRELLI FEDERICA (Presidente)
9 A-L GENETICA 2017/2018 01/10/2017 25/11/2018 LANFRANCHI GEROLAMO (Presidente)
LAVEDER PAOLO (Membro Effettivo)
8 M-Z GENETICA 2016-2017 01/10/2016 30/11/2017 SANDRELLI FEDERICA (Presidente)
7 A-L GENETICA 2016-2017 01/10/2016 30/11/2017 LANFRANCHI GEROLAMO (Presidente)
LAVEDER PAOLO (Membro Effettivo)

Prerequisites: None
Target skills and knowledge: Principles and basic knowledge of the main transmission mechanisms of the hereditary characters . Knowledge on the structure and function of genes , on their interactions as well as on the structure and function of genomes. Through technical practices a direct experience on the use of specific methodologies commonly employed in Genetics will be acquired.
Examination methods: The exam is a written test including exercises of formal genetics, multiple choice and open-ended questions. A question will focus on one of the topics analyzed during the laboratory experience .
Assessment criteria: We will evaluate the ability to solve problems of formal and molecular genetics and to discuss about genetic aspects, with particular attention to the accurate use of terminology, definitions and concepts.
Course unit contents: Introduction to Genetics: The main discoveries in the genetic research. The main branches of genetics: formal, molecular, population and genomics. Basic and applied genetics. Genome structure of phages, Prokaryotes and Eukaryotes. Extranuclear DNAs. Cell division and gene transfer in Prokaryotes. Cell Division in Eukaryotes : mitosis and meiosis.
Formal genetics : definition of genotype , phenotype and norm of reaction; Mendelian inheritance , transmission of autosomal and sex-linked characters. Formal genetic mechanisms at the molecular level. Extending Mendelian inheritance : multiple alleles, lethal alleles, interaction among genes. Penetrance and expressivity. Complementation and allelism test for new mutations. Genetic Mapping in Eukaryotes: two- and three-point mapping with genetic markers. Coefficient of coincidence and interference. Genetic map functions. Advanced genetic mapping in Eukaryotes: analyses in yeast and humans.
Structure and function of the genetic material: DNA replication. Genes coding for proteins. The gene in Prokaryotes and in Eukaryotes: structure, replication, transcription: similarities and differences. The genetic code. Principles on the mRNA translation and synthesis of proteins. Non coding RNAs: Ribosomal RNAs. Transfer RNAs. MicroRNAs: structure and function.
Variations of the gene structure. Chromosomal mutations: Types and Consequences. Gene mutations. Mechanisms and repair systems in Prokaryotes and Eukaryotes. Auxotrophic mutants, use of mutants. Frequency of mutation and evolution .
Planned learning activities and teaching methods: The course includes 48 hours of frontal lecturing and 16 hours of laboratory experience . The theoretical part will be dedicated to the learning and use of the basic principles of formal and molecular genetics. The laboratory experience will be aimed to learn methodologies and techniques commonly used in the discipline of genetics . The laboratory experience will include: 1 ) Analysis of the segregation of a mitochondrial phenotype in the yeast Saccharomyces cerevisiae ; 2 ) Observation and analysis of Drosophila melanogaster mutants; 3 ) Comparative analysis of human metaphases; 4 ) Analysis human pedigrees.
Additional notes about suggested reading: The material used during the frontal lecturing and the laboratory experience will be made available on the e-learning platform.
Textbooks (and optional supplementary readings)
  • Russell, Genetica, Un approccio molecolare. --: Pearson, 2014. Cerca nel catalogo
  • Sanders and Bowman, Genetica, un approccio integrato. --: Pearson, 2013. Cerca nel catalogo
  • Klug, Cummings, Spencer,, Concept of Genetics. --: Pearson, 2014. Cerca nel catalogo