First cycle
degree courses
Second cycle
degree courses
Single cycle
degree courses
School of Medicine
Course unit
FA02101260, A.A. 2018/19

Information concerning the students who enrolled in A.Y. 2016/17

Information on the course unit
Degree course 5 years single cycle degree in
FA1733, Degree course structure A.Y. 2009/10, A.Y. 2018/19
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Number of ECTS credits allocated 8.0
Type of assessment Mark
Department of reference Department of Pharmaceutical and Pharmacological Sciences
Mandatory attendance No
Language of instruction Italian
Single Course unit The Course unit can be attended under the option Single Course unit attendance
Optional Course unit The Course unit can be chosen as Optional Course unit

Teacher in charge STEFANO MORO CHIM/08

ECTS: details
Type Scientific-Disciplinary Sector Credits allocated
Core courses CHIM/08 Pharmaceutical Chemistry 8.0

Course unit organization
Period Second semester
Year 3rd Year
Teaching method frontal

Type of hours Credits Teaching
Hours of
Individual study
Lecture 8.0 64 136.0 No turn

Start of activities 25/02/2019
End of activities 14/06/2019
Show course schedule 2019/20 Reg.2009 course timetable

Examination board
Board From To Members of the board
6 Commissione a.a. 2018/19 01/12/2018 30/09/2019 MORO STEFANO (Presidente)
SISSI CLAUDIA (Membro Effettivo)

Prerequisites: The contents of courses in Pharmaceutical Chemistry 1, Organic Chemistry 1 and 2, and Biochemistry are considered preliminary.
Target skills and knowledge: This course has as its purpose the study of drugs, natural and synthetic, with particular reference to the therapeutic areas of central and peripheral nervous system. The course focuses on the chemical aspects and the chemical-physical properties of the drugs and the relations existing between their structure, their activity and toxicity. Describes in a privileged way the interpretation of molecular interactions between drugs biomolecules involved in their mechanism of action or to induce side effects and toxic.
Examination methods: Examination is performed by an interview with the student that takes place at the end of the training course.
Assessment criteria: The evaluation of profit involves an assessment of the student's critical skills to describe the chemical-physical and pharmaceutical characteristics that characterize an active principle from a pharmacodynamic, pharmacokinetic and toxicological point of view. Particular emphasis will be given to the description and interpretation of the structure-activity relationships (SAR) characterizing the different classes of drugs.
Course unit contents: The course is divided into a general part preparatory to a second part more systematics.

The topics covered can be summarized as:
1. General Part
a. Thermodynamic bases of drug-receptor recognition
b. cellular communication systems

2. Systematic part
a. Cholinergic system
b. Adrenergic system
c. Dopaminergic system
d. Serotoninergic system
e. Histaminergic system
f. Gabaergic system
g. Glutamataeric system
f. Anandaminergic system
Additional notes about suggested reading: All the material presented and discussed in class can be found on the following web page, within the eLearning section:
Textbooks (and optional supplementary readings)
  • Gasco, Gualtieri, Melchiorre, Chimica farmaceutica. --: Casa Editrice Ambrosiana, 2015. Testo di consultazione Cerca nel catalogo
  • Foye, William O.; Williams, David A.; Lemke, Thomas L.; Dall'Acqua, Francesco; Roche, Victoria F.; Zito, S. William, Foye╩╝s principi di chimica farmaceuticaa cura di Thomas L. Lemke, David A. Williamscon la collaborazione di Victoria F. Roche, S. William Zito. Padova: Piccin, 2014. Testo di consultazione Cerca nel catalogo

Innovative teaching methods: Teaching and learning strategies
  • Case study
  • Interactive lecturing
  • Questioning
  • Auto correcting quizzes or tests for periodic feedback or exams
  • Loading of files and pages (web pages, Moodle, ...)

Innovative teaching methods: Software or applications used
  • MMStools

Sustainable Development Goals (SDGs)
Good Health and Well-Being Quality Education