
Course unit
ANALYTICAL CHEMISTRY AND STATISTICAL ELEMENTS
FAL1000980, A.A. 2017/18
Information concerning the students who enrolled in A.Y. 2016/17
ECTS: details
Type 
ScientificDisciplinary Sector 
Credits allocated 
Basic courses 
CHIM/01 
Analytical Chemistry 
8.0 
Course unit organization
Period 
First semester 
Year 
2nd Year 
Teaching method 
frontal 
Type of hours 
Credits 
Teaching hours 
Hours of Individual study 
Shifts 
Lecture 
8.0 
64 
136.0 
No turn 
Start of activities 
02/10/2017 
End of activities 
19/01/2018 
Examination board
Board 
From 
To 
Members of the board 
6 Commissione a.a.2017/18 
01/12/2017 
30/09/2018 
DURANTE
CHRISTIAN
(Presidente)
FERRANTE
CAMILLA
(Membro Effettivo)
DI MARCO
VALERIO
(Supplente)

Prerequisites:

general and inorganic chemistry 
Target skills and knowledge:

At the end of the class the student should be able to:
Evaluate the pH and the concentrations of substances at chemical equilibrium in water solution. In particular acids, bases, mixtures of acids and bases, polyprotic acids and amphiprotic substances.
Calculate the concentrations at equilibrium when complexation, precipitation and redox reactions take place, and also when there is competition between different equilibria.
Know how to read the distribution diagrams as a function of pH and pL.
Have some notions of the utility of these calculations in the pharmacological field.
Know the behaviour of water solutions.
Learn the gravimetric method.
Understand the titration technique, the shape of titration curves and how they can change because of the experimental conditions.
Find the end point in a titration through colorimetric indicators and with the potentiometric method.
Know the principal electrodes most commonly used: glass electrode, redox electrodes, ionselective electrodes.
Learn the two categories of errors affecting experimental measurements and how to recognise them and take care of them.
Know the gaussian and Student distributions, the statistical treatment of repeated measurements using the two distributions aforementioned, the error propagation law.
Learn the use of significant digits.
Make simple statistical decisions when experimental values are compared with reference values.
Learn the least square method to evaluate the equation of a line. 
Examination methods:

The final exams is a written text and aims at assessing the achievement of the previous stated goals by the student. This written examination may also be replaced by partial tests made during the semester. The exam lasts 2 hours, and the student will solve some exercises on chemical equilibria (acidbase, complex, redox, etc.) and multiplechoice questions.
The student must enrol to the exam in UNIWEB. Registration is mandatory, if the students want to register the exam afterward. The list closes 23 days before the date of the exam. If the registered student cannot be present to the exam after registration, he/she should cancel the registration on UNIWEB, or send an email to the teacher warning for his/her his absence.
and some exercises. 
Assessment criteria:

The ability of the student to solve the exercise will give to the teachers the possibility to ascertain the skills acquired by the student in the class. The multiplechoice questions, instead allow testing the overall preparation of the students. 
Course unit contents:

The teaching subjects are divided in three parts:
Part One
General properties of chemical equilibria and equilibrium constant. Le Chatelier Principle. Reaction in water solution: acidbase, complexation, precipitation, and redox. General treatment for the calculation of the concentration of different substances in solution at equilibrium taking care of competitive reactions. Reasonable approximations: how to apply and verify them. Distribution diagrams as a function of pH and pL. Pharmacological applications.
Part Two
Aims and Methods of analytical chemistry: gravimetric analysis, titrations: acidbase, complex formation, precipitation and redpd. Titration curves. How to find the equivalent point through visual methods (colorimetric dyes) and instrumental methods (electrodes). Potentiometry. Glass electrode, ionselective electrode, electrode of first and second kind, redox electrodes. First notions on instrumental analytical techniques.
Third Part
Random and systematic errors. Statistics applied to chemical analysis and definitions of: average, standard deviation, range and confidence interval, uncertainty. Significant Digits. Error propagation law. Statistical decisions. Linear regression with least square method. 
Planned learning activities and teaching methods:

Lectures last for 8 CFU (64 hours) and they are tought in class. The teaching will concern both theoretical explanations and exercise resolution. The lectures will be resumed in powerpoint slides made available to the students by the teachers. They can be used as the basic textbook to prepare the exam. 
Additional notes about suggested reading:

Slides given by the teacher.
Analytical chemistry books available in the library can be used to integrate the slides. 
Textbooks (and optional supplementary readings) 

Daniel C. Harris, Elementi di Chimica Analitica. : Zanichelli, . Consultazione

Tissue, Basic of analytical chemistry. : WileyVCH, 2013. Consultazione

V. Di Marco, P.Pastore, G.G. Bombi, Chimica Analitica. : EdiSES, 2015. Consultazione, Testo di Riferimento (Refernece textbook)


