First cycle
degree courses
Second cycle
degree courses
Single cycle
degree courses
School of Medicine
Course unit
MEP3052598, A.A. 2019/20

Information concerning the students who enrolled in A.Y. 2015/16

Information on the course unit
Degree course 5 years single cycle degree in
FA1733, Degree course structure A.Y. 2009/10, A.Y. 2019/20
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Number of ECTS credits allocated 6.0
Type of assessment Mark
Department of reference Department of Pharmaceutical and Pharmacological Sciences
E-Learning website
Mandatory attendance
Language of instruction English
Single Course unit The Course unit CANNOT be attended under the option Single Course unit attendance
Optional Course unit The Course unit can be chosen as Optional Course unit

Teacher in charge GIANFRANCO PASUT CHIM/09

ECTS: details
Type Scientific-Disciplinary Sector Credits allocated
Core courses CHIM/09 Applied Technological Pharmaceutics 6.0

Course unit organization
Period First semester
Year 5th Year
Teaching method frontal

Type of hours Credits Teaching
Hours of
Individual study
Laboratory 2.0 30 20.0 No turn
Lecture 4.0 32 68.0 No turn

Start of activities 30/09/2019
End of activities 18/01/2020
Show course schedule 2019/20 Reg.2009 course timetable

Examination board
Board From To Members of the board
7 Commissione a.a. 2019/20 01/12/2019 30/11/2020 PASUT GIANFRANCO (Presidente)
SALMASO STEFANO (Membro Effettivo)
SCHIAVON ODDONE (Membro Effettivo)
6 Commissione a.a. 2018/19 01/12/2018 30/11/2019 PASUT GIANFRANCO (Presidente)
SALMASO STEFANO (Membro Effettivo)
SCHIAVON ODDONE (Membro Effettivo)

Prerequisites: The student has to possess the basic knowledge of organic chemistry, biochemistry, pharmacology and pharmaceutical technology to get the best results from this teaching course.
Target skills and knowledge: At the end of the teaching course, the student has acquired the theoretical knowledge and practical skills required to assess and understand the different formulation approaches that can increase the effectiveness and safety of biotech drugs. The student learns how to set a formulation of a protein in aqueous solution for injection or a lyophilised form. In addition, the student acquires advanced knowledge of the most used drug delivery systems for therapeutic proteins. In this section, the students are also introduced to the delivery systems for classic low molecular weight drugs discussed in comparison with the same approach for protein delivery. The student will learn the targeting opportunities with antibodies and their role as delivery systems and therapeutic agents.
The practical experience in the laboratory is an integral part of the course. The student gets an immediate feedback by applying the basic concepts of drug delivery introduced in the lectures. In particular, in laboratory experiments, the students learn how to prepare liposomes, hydrogels and polymeric conjugates of enzymes.
Examination methods: The examination will be carried out in writing with questions in English, the student has to answer in English. The student is required to deliver, a week before the date fixed for the examination, the report of the laboratory in which the student includes the results and discussion of the data from the practical experience. The examination will focus on the topics covered in class and on the submitted course program. The Professor can decide to perform the exam in oral form, in English, after a justified request by the student.
Assessment criteria: The evaluation will take into account the specific knowledge of the student in relation to the question asked and, more broadly, to the general knowledge of the subject matter and the ability to link the different scientific themes covered during the course. The exposition clarity of the student will be an additional criterion together with the demonstration of having deepened further the topics covered during the course.
Course unit contents: The course is centred on the development of classic and advanced approach of formulations of biotech drugs. In particular, the issues related to the stability of proteins and the steps that can be implemented to reduce the degradation processes of these entities will be presented together with the methods used for the characterization of the most frequent degradations. Basics will be provided for the definition of the main polymers used in this field and greater emphasis will be devoted to the study of advanced drug delivery systems for proteins, which are proposed as current or future therapeutic applications. The practical part of the course will provide the student with the knowledge necessary to set up some of the most commonly used drug delivery systems.
Planned learning activities and teaching methods: Teaching takes place in English. The teacher promotes participatory didactics of the students through daily interactions in which questions are asked to the students who elaborate and discuss in groups or singularly specific topics and then confront each other. The comparison of similar topics discussed among groups of students helps them develop a critical sense in a more informal environment among course colleagues. Online tests, anonymous and therefore without impact on the assessment, are carried out in class using the students' smartphones in order to review some topics or stimulate the self-assessment of the students.
Additional notes about suggested reading: The slides of the lessons are given as printed copies by the Professors on the Moodle platform. Insights on the issues addressed can be carried out with the recommended texts or with material available in the library or in the catalogues of scientific journals online.
Textbooks (and optional supplementary readings)
  • G.S. Banker, C.T. Rhodes, Modern Pharmaceutics. --: edizione Marcel Dekker, New York, --. Cerca nel catalogo
  • AT Florence, D Attwood, Le basi chimico-fisiche della tecnologia farmaceutica. --: edizione EdiSES - Napoli, --. Cerca nel catalogo
  • Villiers, Melgardt M. de; Aramwit, Pornanong; Kwon, Glen S., Nanotechnology in Drug Delivery. Series: “Biotechnology: Pharmaceutical Aspects”.. --: --, --. Cerca nel catalogo
  • Hillery, Lloyd, Swarbrick, Drug delivery and targeting for pharmacists and pharmaceutical chemists. --: --, --. Cerca nel catalogo

Innovative teaching methods: Teaching and learning strategies
  • Laboratory
  • Problem based learning
  • Working in group
  • Questioning
  • Action learning
  • Problem solving
  • Flipped classroom
  • Auto correcting quizzes or tests for periodic feedback or exams
  • Active quizzes for Concept Verification Tests and class discussions
  • Use of online videos

Innovative teaching methods: Software or applications used
  • Moodle (files, quizzes, workshops, ...)
  • Kahoot

Sustainable Development Goals (SDGs)
Good Health and Well-Being Industry, Innovation and Infrastructure