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Second cycle
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degree courses
School of Medicine
MEDICINE AND SURGERY
Course unit
IMMUNOLOGY
ME14103788, A.A. 2015/16

Information concerning the students who enrolled in A.Y. 2014/15

Information on the course unit
Degree course 6 years single cycle degree in
MEDICINE AND SURGERY (Ord. 2009)
ME1727, Degree course structure A.Y. 2009/10, A.Y. 2015/16
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Degree course track Common track
Number of ECTS credits allocated 6.0
Type of assessment Mark
Course unit English denomination IMMUNOLOGY
Department of reference Department of Medicine
Mandatory attendance
Language of instruction Italian
Branch PADOVA
Single Course unit The Course unit CANNOT be attended under the option Single Course unit attendance
Optional Course unit The Course unit is available ONLY for students enrolled in MEDICINE AND SURGERY (Ord. 2009)

Lecturers
Teacher in charge ALBERTO AMADORI

Mutuating
Course unit code Course unit name Teacher in charge Degree course code
ME14103788 IMMUNOLOGY ALBERTO AMADORI ME1726

ECTS: details
Type Scientific-Disciplinary Sector Credits allocated
Core courses MED/04 General Pathology 6.0

Course unit organization
Period Second semester
Year 2nd Year
Teaching method frontal

Type of hours Credits Teaching
hours
Hours of
Individual study
Shifts
Group didactic activities 0.0 24 0.0 No turn
Lecture 6.0 48 102.0 No turn

Calendar
Start of activities 01/03/2016
End of activities 15/06/2016
Show course schedule 2019/20 Reg.2015 course timetable

Examination board
Board From To Members of the board
4 IMMUNOLOGIA - COMMISSIONE D'ESAME A.A. 2016/2017 01/10/2013 30/12/2018 AMADORI ALBERTO (Presidente)
ROSATO ANTONIO (Membro Effettivo)
ZANOVELLO PAOLA (Membro Effettivo)
3 IMMUNOLOGIA - COMMISSIONE D'ESAME A.A. 2015/2016 01/10/2015 31/12/2019 AMADORI ALBERTO (Presidente)
ZANOVELLO PAOLA (Membro Effettivo)

Syllabus
Prerequisites: A solid background in genetics, cellular biology, molecular biology, anatomy, and histology is strictly required.
Target skills and knowledge: This Course aims at transmitting to MD students all the fundamental notions on the mechanisms that regulate immune system functioning, with special attention to its ability to guarantee the organism’s homestasis against microbial microenvironment. Moreover, this Course will provide MD students with the basic notions about the alterations/dysfunctions that the above mechanisms could undergo to, in order to empower them with the necessary instruments to better understand during their future learning itinerary all the immuno-pathologic conditions that they will frequently encounter in clinical practice.
Examination methods: Multiple choice tests, possibly integrated by a subsequent interview
Course unit contents: The Course is articulated into two phases:
1) A first cycle of lessons where the fundamental components of the immune system will be described; this analytical description of the elements constituting the immune system will be followed by the effort to provide an integrated view of their functioning within the economy of the immune response:
2) A second cycle of lessons will be centered on the mechanisms underlying the different hypersensitivity reactions; in this setting, the clinical pictures deriving from each of them will be alluded.
Planned learning activities and teaching methods: IMMUNOLOGY:
•THE IMMUNE SYSTEM
GENERAL FEATURES
CELLS AND ORGANS
•INNATE IMMUNITY: CELLS, RECEPTORS, MEDIATORS
•THE MAJOR HISTOCOMPATIBILITY COMPLEX (MHC)
GENE ARRANGEMENT
STRUCTURE AND BIOLOGICAL PROPERTIES OF MHC MOLECULES
•ONTOGENESIS OF T AND B CELLS
•ACQUIRED IMMUNITY RECEPTORS: THE T CELL ANTIGEN RECEPTOR (TCR)
STRUCTURE
GENERATION OF TCR AND ANTIBODY DIVERSITY
•ANTIGEN RECOGNITION AND LYMPHOCYTE ACTVATION
ANTIGEN PROCESSING AND PRESENTATION TO T LYMPOCYTES
•ACQUIRED IMMUNITY RECEPTORS: THE ANTIBODIES (Ig)
STRUCTURE
EFFECTOR FUNCTIONS
•THE COMPLEMENT SYSTEM
ORGANIZATION AND ACTIVATION
BIOLOGICAL CONSEQuENCES
•EFFECTOR MECHANISMS OF IMMUNE REACTIONS (CTL, ADCC)
•EFFECTOR PHASES OF IMMUNE RESPONSES
CYTOKINES AND CHEMOKINES
COOPERATION BETWEEN T AND B LYMPHOCYTES
TH1/TH2 POLARIZATION OF T CELLS
HUMORAL RESPONSES
CELL-MEDIATED RESPONSES

IMMUNOPATHOLOGY:
•HYPERSENSITIVITY REACTIONS:
GENERAL FEATURES AND CLASSIFICATION ACCORDING TO GELL AND COOMBS
TYPE I, II, III AND IV HYPERSENSITIVITY
•TOLERANCE AND AUTOIMMUNITY
•TUMOR IMMUNOLOGY
•TRANSPLANTATION IMMUNOLOGY
ELEMENTS ON PRIMARY AND SECONDARY IMMUNODEFICIENCIES
Textbooks (and optional supplementary readings)
  • Janeway, Charles A.; Mowat, Allan; Walport, Mark; Murphy, Kenneth; Travers, Paul, Immunobiologia. Padova: Piccin, 2014. Cerca nel catalogo
  • Abbas, Abul K.; Lichtman, Andrew H.; Sozzani, Silvano; Baker, Alexandra; Baker, David L., Immunologia cellulare e molecolare. Milano: Elsevier, 2012. Cerca nel catalogo
  • Parham, Peter, <<Il>> sistema immunitarioPeter Parham. Napoli: Edises, 2011. Cerca nel catalogo