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degree courses
Second cycle
degree courses
Single cycle
degree courses
School of Medicine
MEDICINE AND SURGERY
Course unit
BLOOD DISEASES 2 (MOD. SMC 4) (Logistica Treviso)
MEP4068220, A.A. 2018/19

Information concerning the students who enrolled in A.Y. 2014/15

Information on the course unit
Degree course 6 years single cycle degree in
MEDICINE AND SURGERY (Ord. 2009)
ME1726, Degree course structure A.Y. 2009/10, A.Y. 2018/19
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Number of ECTS credits allocated 1.0
Type of assessment Mark
Course unit English denomination BLOOD DISEASES 2 (MOD. SMC 4)
Department of reference Department of Medicine
Mandatory attendance
Language of instruction Italian
Branch PADOVA

Lecturers
Teacher in charge FRANCESCO PIAZZA MED/15

Integrated course for this unit
Course unit code Course unit name Teacher in charge
MEP4068214 MEDICAL-SURGICAL SPECIALTIES 4TH GIANPIETRO CARLO SEMENZATO

Mutuated
Course unit code Course unit name Teacher in charge Degree course code
MEP4068220 BLOOD DISEASES 2 (MOD. SMC 4) (Logistica Treviso) FRANCESCO PIAZZA ME1729
MEP4068220 BLOOD DISEASES 2 (MOD. SMC 4) (Logistica Treviso) FRANCESCO PIAZZA ME1728
MEP4068220 BLOOD DISEASES 2 (MOD. SMC 4) (Logistica Treviso) FRANCESCO PIAZZA ME1727

ECTS: details
Type Scientific-Disciplinary Sector Credits allocated
Educational activities in elective or integrative disciplines MED/15 Blood Diseases 1.0

Course unit organization
Period First semester
Year 5th Year
Teaching method frontal

Type of hours Credits Teaching
hours
Hours of
Individual study
Shifts
Group didactic activities 0.0 4 0.0 4
Lecture 1.0 8 17.0 No turn

Calendar
Start of activities 01/10/2018
End of activities 18/01/2019
Show course schedule 2019/20 Reg.2015 course timetable

Examination board
Examination board not defined

Syllabus

Common characteristics of the Integrated Course unit

Prerequisites: Basic knowledge of laboratory medicine, genetics, molecular biology, microbiology, immunology, basic oncology, physiopathology and clinical methodology is essential.
Target skills and knowledge: In terms of hematological and oncological diseases, immune system diseases and rheumatic diseases (locomotion system and connective tissues), at the end of the course the student must demonstrate:
• a suitable knowledge of nosographical, etiopathogenetic, physiopathological, anathomopathological and clinical profiles;
• a suitable ability to recognize, critically interpret and correlate the principal symptoms and physical signals as well as to request and understand the essential laboratory and instrumental procedures;
• a suitable ability to identify conditions requiring the contribution of the specialist in the field.
Examination methods: The evaluation will be made with an oral examination and will be divided in two parts:
Part 1 will deal with Hematology and Medical Oncology disciplines.
Part 2 will concern Clinical Immunology and Rheumatology fields.
Students must register in the lists that will be prepared independently for the two parts.
The result of the examination of each part will be registered by secretariat services and the final score will result from the average of the scores achieved in the two parts.
Assessment criteria: The ability of the student will be evaluated in terms of knowledge, his/her manner to present and discuss the matter.

Specific characteristics of the Module

Course unit contents: 1) DEFINITION, CLASSIFICATION, EPIDEMIOLOGY, PREVENTION AND SOCIOECONOMIC IMPACT. INTERPRETATION OF CLINICAL TRIALS.
2) APPROACH TO THE PATIENT. Clinical evaluation: signs and general and local symptoms (medical history and physical examination); performance status / quality of life.
3) LABORATORY ORGANIZATION. Laboratory evaluation: non specific indexes; organ functionality parameters; hematological analysis; clinical-laboratory correlations.
4) PATHOLOGY AND CLINIC. Etiology, pathogenetic mechanisms and grounds of pathological and clinical features.
5) DIAGNOSTIC PATHWAY
6) PRINCIPLES OF PHARMACOLOGY AND THERAPY of the following diseases:

• Anemias: deficiency anemias, anemias secondary to infection and enzyme deficiencies of the red blood cell and spherocytosis
• Thalassemias and hemoglobin deficiencies
• Stem cell diseases (aplastic anemia, mieloproliferative disorders, paroxysmal nocturnal hemoglobinuria, myelodysplasias). Relations between myelodysplasias and acute leukaemias.
• Acute and chronic leukemias
• Thymomas
• Lymphoproliferative diseases
• Hodgkin and non Hodgkin lymphomas
• Myelomas and other paraproteinemias
• Thrombocytopenias
• Coagulation and thrombosis diseases
The management of the single diseases shall be preceded by a introductory general section that will focus on concepts of general physiopathology and pathological anatomy, of classification issues, of differential diagnosis or therapy basics, peculiar to the specific disciplines:

• fetal and adult hematopoiesis and relative regulation factors;
• hematological ontogenesis, factors of transcription and cytochines involved in hematopoiesis;
• cytogenetic and molecular biology principles of hematological neoplasias
• genetical and biochemical basis of coagulation and fibrinolysis;
• principles of immunophenotype of circulating and bone marrow cells and leukopenias classification.
• differential diagnosis of lymphadenopathies;
• physiopathology and diagnostic of splenomegalies and hypersplenisms;
• emergencies in oncohemathology
• transplantations, with particular reference to bone marrow transplantation
• transfusional therapy: indications, techniques and law regulations.
Textbooks (and optional supplementary readings)