First cycle
degree courses
Second cycle
degree courses
Single cycle
degree courses
Faculty of Veterinary Medicine
VETERINARY MEDICINE
Course unit
SPECIAL PHARMACOLOGY AND VETERINARY CHEMOTHERAPY (CLINICAL MEDICINE)
MVL1001708, A.A. 2013/14

Information concerning the students who enrolled in A.Y. 2011/12

Information on the course unit
Degree course 5 years single cycle degree in
VETERINARY MEDICINE
MV0991, Degree course structure A.Y. 2011/12, A.Y. 2013/14
N0
bring this page
with you
Number of ECTS credits allocated 6.0
Type of assessment Mark
Course unit English denomination SPECIAL PHARMACOLOGY AND VETERINARY CHEMOTHERAPY (CLINICAL MEDICINE)
Website of the academic structure http://www.unipd.it/corsi/corsi-di-laurea/corsi-di-laurea-magistrale/medicina-veterinaria
Department of reference Department of Animal Medicine, Production and Health
Mandatory attendance
Language of instruction Italian
Branch LEGNARO (PD)
Single Course unit The Course unit CANNOT be attended under the option Single Course unit attendance
Optional Course unit The Course unit can be chosen as Optional Course unit

Lecturers
Teacher in charge CLARA MONTESISSA
Other lecturers FRANCESCA CAPOLONGO VET/07

Mutuated
Course unit code Course unit name Teacher in charge Degree course code
MVL1001603 SPECIAL PHARMACOLOGY AND VETERINARY CHEMOTHERAPY (FOOD SAFETY) CLARA MONTESISSA MV0991

ECTS: details
Type Scientific-Disciplinary Sector Credits allocated
Core courses VET/07 Veterinary Pharmacology and Toxicology 6.0

Course unit organization
Period Second semester
Year 3rd Year
Teaching method frontal

Type of hours Credits Teaching
hours
Hours of
Individual study
Shifts
Practice 1.0 10 15.0 No turn
Lecture 5.0 46 79.0 No turn

Calendar
Start of activities 03/03/2014
End of activities 14/06/2014
Show course schedule 2019/20 Reg.2017 course timetable

Examination board
Board From To Members of the board
6 Commissione valida dall'a.a. 2016/17 01/12/2016 30/11/2019 DACASTO MAURO (Presidente)
CAPOLONGO FRANCESCA (Membro Effettivo)
DE LIGUORO MARCO (Supplente)
5 Commissione A.A. 2015/16 01/12/2015 30/11/2016 DACASTO MAURO (Presidente)
CAPOLONGO FRANCESCA (Membro Effettivo)
DE LIGUORO MARCO (Supplente)
4 Commissione A.A. 2014/15 - valida dal 02/03/2015 02/03/2015 30/11/2015 DACASTO MAURO (Presidente)
CAPOLONGO FRANCESCA (Membro Effettivo)
DE LIGUORO MARCO (Supplente)
2 Commissione A.A. 2013/14 01/01/2014 30/11/2014 MONTESISSA CLARA (Presidente)
CAPOLONGO FRANCESCA (Membro Effettivo)
DE LIGUORO MARCO (Supplente)
01/10/2009 31/12/2013 MONTESISSA CLARA (Presidente)
CAPOLONGO FRANCESCA (Membro Effettivo)
DE LIGUORO MARCO (Membro Effettivo)
DACASTO MAURO (Supplente)

Syllabus
Prerequisites: Students must know the fundaments of biochemistry, physiology and pathology of pet animals and food producing species.
They should be informed of the kinetics and dynamics rules that control xenobiotic behaviour in animal bodies and modulate their potency.
(i.e.: specie-specific differences of drug metabolising activities in liver, or drug-receptor interactions)

Propedeutic courses: Veterinary Phisiology and ethology 2; General Pharmacology, Toxicology and Veterinary Drug surveillance
Target skills and knowledge: During the course the action on the different tissues and organs of the main classes of veterinary therapeutic drugs and of main toxicants affecting animal life should be learnt. For each class of drugs and toxicant/contaminants the students should know their main mechanism of action, therapeutic/toxic effects and kinetics further to the correct administration route to single animal (pets) or to farm animals (mass treatment). The rules for the prudent antimicrobial use in pets and in food producing animal should be known and adopted for all the antibacterial drugs used in veterinary practice.
For each class the main adverse effects should be known together with all the information needed to complete the notification form to the competent authorities for drug surveillance.

Student will understand the main environmental or domestic/farm poisons and poisoning outbreaks in small animals and farm animals.For each toxicant species-specific toxicity and antidote therapy should be learnt.
Examination methods: Oral comprehensive examination of the three module programme at the end of the course
Assessment criteria: The students skills on the dynamic and kinetic drug properties in the different veterinary species will be assessed, together with the ability to apply a correct and prudent use of antimicrobials to prevent drug resistance in vet species
The student ability to identify early sign of intoxication, to treat the poisoned animal with antidotal therapy and the knowledge of preventive measures, safe and prudent use of toxic compounds on and around livestock, will be evaluated.
Their awareness of the hazard posed by xenobiotics of various origin (drugs, pesticides, natural and industrial
feed contaminants) to the health of pets and farmed animals, to the safety of products from food producing species,and to the
balance of the environment, will be assessed
Course unit contents: Veterinary chemotherapy 2 CFU
Main dynamic and kinetic aspects and efficacy evaluation by PK/PD approach of the followingdrug classes:
Antibacterials: betalactam antibiotics, aminoglycosides, tetracyclines, phenicols, macrolides, lyncosamides, sulphonamides and fluoroquinolones
Anthelmintics: benzimidazoles derivatives, macrocyclic lactones, arsenicals and miscellanous.
Antifungals: azole derivatives and cell walls inhibitors
Endectocides and Antiparasiticals for external use

Special Pharmacology 2 CFU
Module program
Mechanism of action and main kinetic aspect in vet species will be evaluated for the following pharmacological class of drugs acting on:
CNS injectable and inhalation anaesthetics, analgesic-narcotic drugs, sedatives and anticonvulsant drugs. CNS stimulating drugs. ANS Drugs acting as agonist/antagonist of cholinergic, adrenergic and histamine receptors.
Renal and cardiovascular system: diuretics, ACE inhibitors, digitalis glycosides, anthyarhythmic, vasodilator drugs. Respiratory system: antitussive and bronchodilator drugs Digestive system: antacids, emetics, antiemetics, laxative drugs and dhiarrea management.
Endocrine and metabolism: steroid and non steroid antinflammatory drugs, insulin and synthetic antidiabetic drugs

Special toxicology 2 CFU (clinical) For each toxicant class, the sources of poison, kinetics, dynamics, risk factors, pathology, clinical signs, antidotes and prognosis will be discussed:
Household and Industrial products (detergents, acids, alkali, ethylene glycol, phenols); Rodenticides (anticoagulant rodenticides, bromethalin, cholecalciferol, sodium fluoroacetate, strychnine, Zinc phosphide); Organochlorine Insecticides, Pyrethrines and Pyrethroids Anticholinesterase Insecticides, Molluschicides, Dipyridil Herbicides, alcaloids and other organic compounds from toxic Plants. vet Drugs AINS and paracetamol, Methylxantines, Antiparasiticals)
toxic compound of house plants

In alternative

Special toxicology 2 CFU (Food safety)
Legal and illegal drug use in farm animals: toxicological risks for livestock (overdosages, intolerances) for environment(environmental impact) and for consumers (residues in food of animal origin).
Natural contaminants of feed: mycotoxins and phytotoxins.
Industrial contaminants: dioxins, PCBs, heavy metals
Accidental or intentional acute intoxications from insecticides, herbicides, rodenticides, urea and nitrates
Carcinogens in food of animal origin: PAHs and N-nitroso compounds
Planned learning activities and teaching methods: Lectures 4 CFU with Powerpoint support

Class practice: 1 CFU
Discussion of scientific paper dealing with kinetics, dynamics,therapeutical protocol and administration route of veterinary medicinal products
Compilation of a notification form of adverse drug reaction

(clinic and food safety)
lectures = 46
practical activities = 10
Additional notes about suggested reading: All slides used for lectures presentation (powerpoint.file or pdf. file) will be available on Moodle platform https://elearning.unipd.it/scuolaamv/)

other material will be given directly to the student on request.
Textbooks (and optional supplementary readings)
  • Carli S., Ormas P., Re G., Soldani G., Farmacologia veterinaria. Napoli IT: Idelson-Gnocchi Editore. ISBN 978-88-7947-484-9, 2009. ISBN 978-88-7947-484-9
  • Guardabassi G., Jensen L.B., kruse H., A guide to Antimicrobial Use in Animals. Oxford UK: Blackwell Publishing LTD, 2008. ISBN 978- 1- 4051-5079-8 Cerca nel catalogo
  • Nebbia C, Residui di farmaci e contaminanti ambientali nelle produzioni animali. Napoli: EDISES, 2009. Cerca nel catalogo
  • M.E. Peterson and P.A. Talcott, Small animal toxicology. San Louis M0 - USA: Elsevier-Saunders -, 2012. III ed Cerca nel catalogo