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MUCIGNAT CARLA
Contacts
Notice and additional information
La docente può essere contattata utilizzando l'indirizzo e-mail istituzionale: carla.mucignat@unipd.it
Office hours
(updated on 28/04/2017 10:18)
Proposals for thesis
Please contact me.
Curriculum Vitae
Born in Pordenone (Italy) on October 16, 1966.
1988:degree in Psychology, University of Padova. Results published in: Bisiacchi P., Marzi C.A., Nicoletti R., Carena G., Mucignat C., Tomaiuolo F. (1994) Left-right asymmetry of callosal transfer in normal human subjects, Behav. Brain Res. 64, 173-178 1993: Ph.D. in Neurosciences, University of Parma, Italy. Results published in: Mucignat-Caretta C., Caretta A., Cavaggioni A. (1995) Acceleration of puberty onset in female mice by male urinary proteins, J. Physiol. 486, 517-522 October 1993: research at Mammalian Reproduction Group (Prof. A. Marchlewska-Koj), Universitas Jagellonica, Krakow (Poland). 1994-1997: post-doc at Istituto di Fisiologia Umana, Università di Parma. Since 1997: Technician at the Istituto di Fisiologia Umana, Università di Padova. Since 2001:Lecturer in Physiology, Dipartimento di Anatomia e Fisiologia Umana, Facoltà di Medicina e Chirurgia dell’Università di Padova, SSD BIO/09. Since 2007: Associate Professor of Physiology (SSD BIO/09), Dipartimento di Medicina Molecolare dell’Università di Padova. TEACHING DUTIES 1995-1996: Assistant Professor, school of Psychology, University of Bologna. Since 1997 she taught: Physiology, Neurophysiology, Psychobiology in different courses at the School of Medicine, University of Padova. 2003 to 2005: Master in "Etologia applicata e benessere animale" (University of Bologna and Padova). Since 2005 she taught Physiology to Medical residents in: Medicina dello Sport, Scienza dell'Alimentazione, Ortognatodonzia, Medicina Fisica e Riabilitativa. SCIENTIFIC ACTIVITY At the beginning she worked in neuropsychology, studying stimulus processing and attention. Then she worked on chemical communication in mammals, in particular in mice. She also collaborated to the immunohistochemical description the vomeronasal organ. She also studied protein kinase A in the brain of different animal models of neurological diseases, besides human tissue. Member of Società Italiana di Neuroscienze, Società Italiana di Scienze Sensoriali and European Chemoreceptor Research Organization. Reviewer for more than 40 international scientific journals. Reviewer for funding calls for MIUR, EC (VII° Framework Program ), Austrian Science Fund, Israel Science Foundation. Ha ottenuto finaziamenti da: Università di Padova (Progetti di Ateneo, ex-60%), MIUR (PRIN), EU VI e VII Programma Quadro. Research areas
1. Comunicazione feromonale nei topi.
Definizione degli stimoli: purificazione e sintesi. Definizione delle risposte comportamentali e fisiologiche. Studio dei sistemi chemosensoriali. 2. Sensori chimici. Utilizzo di un approccio biomimetico alla costruzione di sensori chimici. 3. Neurofisiologia dello sviluppo e dell'invecchiamento. Analisi delle vie di segnalazione intracellulare mediate dall'adenosimonofosfato ciclico durante lo sviluppo pre- e postnatale, sino all'età avanzata. 4. Modelli animali di patologie: studi comportamentali, biochimici ed anatomici. Patologie neurologiche. Tumori dell'encefalo. Publications
Selected papers 1995-2004
Mucignat-Caretta C., Caretta A., Cavaggioni A. (1995) Acceleration of puberty onset in female mice by male urinary proteins. J Physiol. 486, 517-522 Tirindelli R., Mucignat-Caretta C., Ryba N.J.P. (1998) Molecular aspects of pheromonal communication via the vomeronasal organ of mammals. Trends Neurosci. 21, 482-486 Mucignat-Caretta C., Caretta A. (1999) Urinary chemical cues affect light-avoidance behaviour in male laboratory mice, Mus musculus. Anim Behav. 57, 765-769 Mucignat-Caretta C. (2000) Aggregates of cAMP-dependent kinase RIα characterize a type of cholinergic neurons in the rat brain. Mol Brain Res. 80, 233-236 Cavaggioni A., Mucignat-Caretta C. (2000) Major Urinary Proteins, α2U-globulins and aphrodisin. Biochim Biophys Acta-Protein Struct Mol Enzymol. 1482, 218-228 Mucignat-Caretta C., Caretta A. (2002) Clustered distribution of cAMP-dependent protein kinase regulatory isoform RIalpha during the development of the rat brain. J Comp Neur. 451, 324-333 Mucignat-Caretta C. (2002) Modulation of exploratory behavior in female mice by protein-borne male urinary molecules. J. Chem. Ecol. 28, 1853-1863 Mucignat-Caretta C., Caretta A. (2004) Regional variations in the localization of insoluble kinase A regulatory isoforms during rodent brain development. J Chem Neuroanat. 27, 201-212 Mucignat-Caretta C, Bondi’ M, Caretta A (2004) Animal models of depression: olfactory lesions affect amygdala, subventricular zone and aggression. Neurobiol Dis. 16, 386-395 Mucignat-Caretta C, Bondi’ M, Caretta A (2004) Endocrine status affects bladder size and post-void residual urinary volume in mice. Horm Behav., 46, 11-18 Selected papers 2005-2012 Bigiani A, Mucignat-Caretta C, Montani G, Tirindelli R (2005) Pheromone reception in mammals. Rev Physiol Biochem Pharmacol. 154, 1-35 Mucignat-Caretta C, Colivicchi MA, Fattori M, Ballini C, Bianchi L, Gabai G, Cavaggioni A, Della Corte L (2006) Species-specific chemosignals evoke delayed excitation of the vomeronasal amygdala in freely-moving female rats. J Neurochem. 99, 881-891 Mucignat-Caretta C, Caretta A (2007) Distribution of insoluble cAMP-dependent kinase type RI and RII in the lizard and turtle central nervous system. Brain Res. 1154, 84-94 Mucignat-Caretta C, Cavaggioni A, Redaelli M, Malatesta M, Zancanaro C, Caretta A (2008) Selective distribution of protein kinase A regulatory subunit RIIalpha in rodent gliomas. Neuro Oncol. 10:958-967 Mucignat-Caretta C, Bondí M, Rubini A, Calabrese F, Barbato A (2009) The olfactory system is affected by steroid aerosol treatment in mice. Am J Physiol Lung Cell Mol Physiol. 297:L1073-1081 Mucignat-Caretta C, Denaro L, Redaelli M, D'Avella D, Caretta A. (2010) Protein kinase A regulatory subunit distribution in medulloblastoma. BMC Cancer. 10:141 Mucignat-Caretta C (2010) The rodent accessory olfactory system. J Comp Physiol A. 196:767-777 Zagotto G, Redaelli M, Pasquale R, D'Avella D, Cozza G, Denaro L, Pizzato F, Mucignat-Caretta C (2011) 8-Hydroxynaphthalene-1,4-dione derivative as novel compound for glioma treatment. Bioorg Med Chem Lett. 21:2079-2082 Mucignat-Caretta C, Caretta A (2011) Aggregates of cAMP-dependent kinase isoforms characterize different areas in the developing central nervous system of the chicken, Gallus gallus. Dev Neurosci. 33:144-158 Mucignat-Caretta C, Redaelli M, Caretta A (2012) One nose, one brain: contribution of the main and accessory olfactory system to chemosensation. Front Neuroanat. 6, 46 List of taught course units in A.Y. 2017/18
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