DE ZOTTI MARTA

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Structure Department of Chemical Sciences
Telephone 0498275280
Qualification Ricercatore a tempo determinato di tipo A
Scientific sector CHIM/06 - ORGANIC CHEMISTRY
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Proposals for thesis
Argomento 1: Chimica biorganica

Il progetto di Tesi prevede la sintesi e lo studio conformazionale di peptidi naturali e loro analoghi ad attività antibatterica e/o antitumorale.
I peptidi in esame, ricchi in amminoacidi naturali non proteinogenici, sono naturalmente resistenti alla degradazione enzimatica e adottano strutture elicoidali stabili.

Argomento 2: Chimica organica applicata ai materiali

Il progetto prevede lo sviluppo di sistemi a base peptidica in grado di modificare la loro conformazione in risposta a stimoli esterni come il cambio di pH o di solvente. I sistemi prodotti verranno ancorati a vari tipi di superfici in modo da studiarne le proprietà elastiche ed elettroniche. Applicazioni di queste MOLLE MOLECOLARI vanno dalla sensoristica ai biomateriali.

Curriculum Vitae
2000: 7 months at NTNU (Norway) with ERASMUS and NTNU fellowships: enzyme catalyzed organic reactions.
2002: Master degree (Laurea) in Chemistry.
2006: Stage at Giessen University (Germany): advanced peptides' characterization.
2007: Stage at Chosun University (South Korea): peptides' proteolysis and bioactivity.
2007: Ph.D. in Chemistry.
2007-2011: post-doc: membrane active peptaibols, synthesis and study.
2011-2013: Senior post-doc activity – University of Padova.
2012: Post-doc at Manchester University (UK, Prof. J.Clayden): advanced organic syntheses.
2014-present: RTD-A. Non-permanent researcher. Principal Investigator of a Future in Research Natonal Project.

2003-present: Participant in national funding projects.

Research Activity:
Organic Chemistry. Synthesis of peptides containing non-coded amino acids. Spectroscopical studies. Conformational analysis (CD, FT-IR, 2D-NMR, MD calculations, X-ray diffraction).

Research Interests:
ANTIMICROBIAL/ANTITUMOR PEPTIDES
PEPTIDE-BASED MOLECULAR DEVICES: TOWARDS NEW SMART MATERIALS.

Scientific contributions:
Co-author of more than 55 publications on ISI journals (four as corresponding author) and of more than 30 European/American Peptide Symposium Proceedings. 7 oral (2 invited) and about 40 poster communications presented at national and international meetings. Reviewer for ISI journals. H-index: 14.

Lecturer's Curriculum (PDF): 88A3D5BDB4C2F2A4658971F21CEA547C.pdf

List of taught course units in A.Y. 2017/18
Degree course code Degree course track Course unit code Course unit name Credits Year Period Lang. Teacher in charge
AG0061 COMMON AG02122097 BASIC PRINCIPLES OF INORGANIC AND ORGANIC CHEMISTRY
A.Y. 2017/18 details
8 1st Year First
semester
ITA MARTA DE ZOTTI