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Structure Department of Comparative Biomedicine and Food Science
Telephone 0498272589
Qualification Professore associato confermato
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Office hours
Wednesday from 12:00 to 13:00 Agripolis 1° stecca 1° piano Dipartimento di Biomedicina Comparata e Alimentazione Previo appuntamento telefonico 049 8272589 o via mail
(updated on 23/04/2018 11:58)

Curriculum Vitae
1. Educational and professional path
Graduated in Biology in 1998 at the University of Padua, Researcher in Anatomy of Domestic Animals since 2005, Associate Professor (SSD VET/01) since May 2015.
2. Scientific activity
From the post-graduate period at the Genetics laboratory of the Biology Department to date she has dealt mainly with genetics and molecular biology, from the study of population genetics to the characterization of some genes involved in skeletal muscle myogenesis and study of their expression in different organisms such as: marine invertebrates, teleost fishes, some mammals of veterinary interest, such as pigs, cattle and dogs, and in the last period, also man.
3. Educational activity
- "Veterinary Anatomy" 6 ECTS (40 hours frontal + 8 hours practice) Bachelor's Level Degree in Safety and hygiene of food products (from a.y.2004/2005)
- "Anatomy of farm animals" 1 ECTS (8 hours practice) Bachelor's degree course in Animal sciences and technologies (from a.y. 2016/2017)
- "General and Comparative Animal Physiology, Anatomy and Embryology" 4 ECTS(32 hours frontal) Bachelor's Degree in Biotechnology (from a.y. 2017/2018)
4. Management activity in University Committee
Didactic Committee for Bachelor's Level Degree in Safety and hygiene of food products

Research areas
- Isolation of genes encoding some growth factors belonging to the IgF (I and II) family and to the IgF-binding proteins in two species of marine teleost fish, Sparus aurata and Umbrina cirrosa, and to study their gene expression in different tissues through the production of specific RNA probes for in situ hybridization reactions on sections of frozen or paraffin-embedded tissues. She has also extended the study of expression through histochemical and immunohistochemical techniques on paraffin-embedded samples

- Study of gene expression of different myosin heavy chain isoforms (slow, 2A, 2B, 2X, alpha-cardiac, neonatal, embryonic, and extraocular) in different muscles with different composition in fiber types in mammalian of particular veterinary interest, such as pig, cattle and dog, and in humans, through molecular techniques, from total RNA extraction (PCR, in situ hybridization), immunochemistry and qualitative PCR (RT-PCR) and quantitative techniques (RealTime PCR)

- Study of the qualitative and quantitative expression of myogenic MRFs growth factors, among which MyoD, Myf5 MRF4, MSTN, Pax7, CD34, in fetuses and during the postnatal development phases, in the pig. Cellular localization of these factors mediating in situ hybridization and preparation of primary cell cultures from muscle tissue

- Study of the congenital pseudomyotonia of the Chianina breed of cattle as an experimental model for the study of the pathogenesis of Brody's human disease. The mutation in the ATP2A1 gene encoding the SERCA1 protein has been indicated as the cause of the disease

Scientific publications from 2007:
Maccatrozzo L., et al.(2007) Genomics. 89, 224–236.
Poltronieri C., et al. (2007) European Journal of Histochemistry 51, 125-135.
Toniolo L., et al. (2007) AJP: Cell Physiology 292: C1915-C1926.
Patruno M., et al. (2008) Myostatin shows a specific expression pattern in pig skeletal and extraocular muscles during pre- and post-natal growth. Differentiation 76, 168-181.
Patruno M., et al. (2008) Real-time polymerase chain reaction, in situ hybridization and immunohistochemical localization of insulin-like growth factor-I and myostatin during development of Dicentrarchus labrax (Pisces: Osteichthyes). Cell And Tissue Research 331, 643-658.
Mascarello F., et al. (2008) Proteins involved in calcium homeostasis expressed in horse cardiomyocytes. Veterinary Research Communications 32(Suppl 1), S159-S162.
Toniolo L., et al. (2008) Masticatory myosin unveiled: first determination of contractile parameters of muscle fibers from carnivore jaw muscles. American Journal of Physiology. Cell Physiology 295 (6), 1535-1542.
Mascarello F., et al. (2009) Phenotypic expression of 2b myosin heavy chain isoform: a comparative study among species and different muscles. Veterinary Research Communications 33(Suppl 1), 105-107.
Martinello T., et al. (2010) Cryopreservation does not affect the stem characteristics of multipotent cells isolated from equine peripheral blood. Tissue Eng Part C Methods 16 (4), 771-781.
Martinello T., et al. (2011) Canine adipose-derived-mesenchymal stem cells do not lose stem features after a long-term cryopreservation. Research in Veterinary Science 91(1), 18-24.
Sacchetto R., et al. (2012) Overexpression of histidine-rich calcium binding protein in equine ventricular myocardium. Vet J 193(1):157-61.
Martinello T. et al. (2012) Successful recellularization of human tendon scaffolds using adipose-derived mesenchymal stem cells and collagen gel. J Tissue Eng Regen Med. In press doi: 10.1002/term.1557.
Nadjar-Boger E., et al. (2013) Genomic cloning and promoter functional analysis of myostatin-2 in shi drum, Umbrina cirrosa: conservation of muscle-specific promoter activity. Comp Biochem Physiol B Biochem Mol Biol 164(2):99-110.
La Rovere R. M., et al. (2014) Myogenic potential of canine craniofacial satellite cells. Frontiers in Aging Neuroscience 6, 90.
Boscolo Papo M., et al. (2014) Expression of CYP4 and GSTr genes in Venerupis philippinarum exposed to benzo(a)pyrene. Annals of Anatomy 196 (4), 241-6.
Martinello T, et al. (2014) Successful recellularization of human tendon scaffolds using adipose-derived mesenchymal stem cells and collagene gel. Journal of Tissue Engineering and Regenerative Medicine 8 (8), 612-9.
Mascarello F, et al. (2016) Expression and identification of 10 sarcomeric MyHC isoforms in human skeletal muscles of different embryological origin. Diversity and similarity in mammalian species. Ann Anat. 207:9-20.
Spaas JH, et al. (2016) Wound-healing markers after autologous and allogeneic epithelial-like stem cell treatment. Cytotherapy. 18(4):562-9.
Valle G, et al. (2016) Characterization of fast-twitch and slow-twitch skeletal muscles of calsequestrin 2 (CASQ2)-knock out mice: unexpected adaptive changes of fast-twitch muscles only. J Muscle Res Cell Motil. 37(6):225-233.
M. R. Pastore, et al. (2018) Effects of dietary soy isoflavones on estrogenic activity, cortisol level, health and growth in rainbow trout, Oncorhynchus mykiss. Aquaculture Res 49(4): 1469–1479)

List of taught course units in A.Y. 2018/19
Degree course code Degree course track Course unit code Course unit name Credits Year Period Teacher in charge
IF0325 000ZZ AGN1029478 ANATOMY OF LARGE ANIMALS 8 1st Year Second semester ROBERTA SACCHETTO
MV1734 000ZZ MVL1001703 VETERINARY ANATOMY 6 1st Year First semester LISA MACCATROZZO

Responsibility of other activity for A.Y. 2018/19
Degree course code Degree course track Course unit code Course unit name Credits Year Period Teacher in charge
MV1734 000ZZ MV02105165 ENGLISH LANGUAGE 3 1st Year First semester LISA MACCATROZZO