First cycle
degree courses
Second cycle
degree courses
Single cycle
degree courses
School of Medicine
MEDICAL BIOTECHNOLOGIES
Course unit
PHARMACEUTICAL BIOTECHNOLOGY: DESIGN AND ANALYSIS OF BIOPHARMACEUTICALS
MEO2045674, A.A. 2017/18

Information concerning the students who enrolled in A.Y. 2017/18

Information on the course unit
Degree course Second cycle degree in
MEDICAL BIOTECHNOLOGIES
ME1934, Degree course structure A.Y. 2012/13, A.Y. 2017/18
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Degree course track MEDICAL BIOTECHNOLOGIES [002PD]
Number of ECTS credits allocated 6.0
Type of assessment Mark
Course unit English denomination PHARMACEUTICAL BIOTECHNOLOGY: DESIGN AND ANALYSIS OF BIOPHARMACEUTICALS
Department of reference Department of Molecular Medicine
Mandatory attendance No
Language of instruction English
Branch PADOVA

Lecturers
Teacher in charge CLAUDIA SISSI CHIM/08

Mutuated
Course unit code Course unit name Teacher in charge Degree course code
MEO2045674 PHARMACEUTICAL BIOTECHNOLOGY: DESIGN AND ANALYSIS OF BIOPHARMACEUTICALS CLAUDIA SISSI ME1934

ECTS: details
Type Scientific-Disciplinary Sector Credits allocated
Core courses CHIM/08 Pharmaceutical Chemistry 6.0

Mode of delivery (when and how)
Period First semester
Year 1st Year
Teaching method frontal

Organisation of didactics
Type of hours Credits Hours of
teaching
Hours of
Individual study
Shifts
Laboratory 2.0 30 20.0 No turn
Lecture 4.0 32 68.0 No turn

Calendar
Start of activities 02/10/2017
End of activities 19/01/2018

Syllabus
Prerequisites: none
Target skills and knowledge: Basic knowledge on advanced techniques used to perform a qualitative and quantitative characterization of naturally occurring biomolecules (proteins, polysaccharides and nucleic acids).
In particular the course will Introduce the students to the design, production and use of biodrugs.
Examination methods: The final exam will be written
Assessment criteria: the student will be evaluated on its abitiies to criticallly correlated the main topics dicussed duringthe course
Course unit contents: Biodrugs: basic concept; production; purification; storage Evaluation of the potential application of pharmacologically active macromolecules
Optimization of pharmacologically active macromolecules
combinatorial approaches
relevant examples (enzymes, hormones, antibodies, nucleic acids)
Data analysis
electrophoretic tecniques (2D; sequencing, EMSA,CE)
Spectroscopic tecniques (CD, Fret, fluorescence quencing)
MIcrocalorimetric tecniques (ITC, DSC)
Biosensors (SPR)
computational tools
Planned learning activities and teaching methods: A main module of teaching will provide the basic concept.
This will be inegrated with
- practical experience on some analitical techniques
- example of critical reading of literature papers
- lessons hold by experts in selected topics
Additional notes about suggested reading: All the slides presented during the couse will be provided.
In additions literature papers will be suggested during the lessons
Textbooks (and optional supplementary readings)