First cycle
degree courses
Second cycle
degree courses
Single cycle
degree courses
School of Engineering
BIOENGINEERING
Course unit
MEDICAL BIOTECHNOLOGIES
INP6075697, A.A. 2017/18

Information concerning the students who enrolled in A.Y. 2016/17

Information on the course unit
Degree course Second cycle degree in
BIOENGINEERING
IN0532, Degree course structure A.Y. 2011/12, A.Y. 2017/18
N0
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Number of ECTS credits allocated 6.0
Type of assessment Mark
Course unit English denomination MEDICAL BIOTECHNOLOGIES
Department of reference Department of Information Engineering
Mandatory attendance No
Language of instruction English
Branch PADOVA

Lecturers
Teacher in charge ENRICO LAVEZZO

ECTS: details
Type Scientific-Disciplinary Sector Credits allocated
Educational activities in elective or integrative disciplines MED/07 Microbiology and Clinical Microbiology 6.0

Mode of delivery (when and how)
Period First semester
Year 2nd Year
Teaching method frontal

Organisation of didactics
Type of hours Credits Hours of
teaching
Hours of
Individual study
Shifts
Lecture 6.0 48 102.0 No turn

Calendar
Start of activities 25/09/2017
End of activities 19/01/2018

Syllabus
Prerequisites: Basic knowledge of biology and physiology. In particular, knowledge about structure and function of DNA, RNA and protein syntesis in eukariotic and prokariotic cells is required.
Target skills and knowledge: Basic information about the fundamental technologies applied in the field of medical biotechnologies (e.g. molecular cloning, generation of genomic libraries, methods for DNA amplification and sequencing, whole genome sequencing, immunological techniques, gene editing, gene therapy, vaccine development, cell reprogramming, tissue engineering) and their application to diagnosis and therapy of human diseases.
Examination methods: Written test.
Assessment criteria: Students will be evaluated based on their understanding and competence regarding the proposed topics, besides the ability of generalization of concepts with critical thinking.
Course unit contents: 1: Basic technologies
- molecular cloning
- genomic libraries
- DNA amplification through PCR
- DNA sequencing methods
- whole genome sequencing
- DNA and protein alignment methods

2: Diagnosis and therapy of human diseases:
- molecular diagnosis
- immunological approaches to detect protein biomarkers of disease
- molecular approaches for disease diagnosis
- RNA detection as a method for disease diagnosis

3: Basic concepts in Immunology:
- immune response
- immune system functions
- types of antibodies: applications
- immunological techniques

4: Microbiology:
- bacteria
- viruses

5: Production of therapeutic agents:
- gene expression manipulation in prokaryotes
- production of heterologous proteins in eukaryotic cells
- site-specific mutagenesis
- genome editing
- mRNA and DNA specific targeting
- viral and non-viral systems for gene transfer
- gene therapy and applications

6: Vaccines:
- vaccination
- subunit vaccines
- DNA vaccines
- attenuated vaccines
- vaccine vectors

7: Cell therapy:
- stem cell biology
- stem cell reprogramming
- tissue engineering
Planned learning activities and teaching methods: The course introduces theoretical backgrounds through frontal lessons, which will be as interactive as possible to promote a high degree of participation from the students.
Additional notes about suggested reading: The teaching material will be exclusively in english. The slides of each lecture will be provided, together with scientific reviews on specific subjects.
Textbooks (and optional supplementary readings)